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Feasibility and impact of sentinel lymph node biopsy in patients affected by ano-rectal melanoma.
Tech Coloproctol
January 2025
Department of Surgical Sciences, University of Turin, Turin, Italy.
Introduction: Anorectal melanoma (ARM) is rare and highly lethal neoplasm. It has a poorer prognosis compared with cutaneous ones. Sentinel lymph node biopsy (SLNB) has become the preferred method of nodal staging method for cutaneous melanoma.
View Article and Find Full Text PDFEpidemiology and outcomes of gastrointestinal mucosal melanomas: a national database analysis.
BMC Gastroenterol
April 2022
The Wright Center for Graduate Medical Education, 501 S. Washington Avenue, Scranton, PA, 18503, USA.
Aim: Gastrointestinal malignant melanoma is a rare mucosal melanoma (MM). Other MM include the respiratory and the genitourinary tract. All mucosal melanomas have a poor prognosis when compared to cutaneous melanomas.
View Article and Find Full Text PDFMDCT evaluation of synchronous breast carcinoma and other solid malignancies.
Breast Dis
January 2022
Radiology Department, Mansoura University Faculty of Medicine, Mansoura, Dakahlya, Egypt.
Background: Multiple primary malignancies are two or more malignancies in an individual without any relationship between the tumors. The development of improved diagnostic techniques, increased survival of cancer patients and the growing life expectancy have all contributed to the increased frequency of this phenomenon.
Objective: The aim of this study is to review the multidetector computed tomography (MDCT) findings of synchronous breast carcinoma and other solid malignancies.
Malignant melanoma of urethra in a young female - Case report and Literature review.
Gulf J Oncolog
January 2021
Dept. of Pathology, Jawaharlal Institute of Post Graduate Medical Education & Research (JIPMER), Puducherry.
Malignant mucosal melanoma (MM) is a rare and aggressive neoplasm, which behaves differently from its cutaneous counterpart. MM of head and neck account for 55.4%, genital tracts - 18%, ano-rectal - 23.
View Article and Find Full Text PDFIdentification of PKHD1 mutations in Brain, Breast and Rectal tumors by Next Generation DNA Sequencing.
Gulf J Oncolog
January 2021
Departments of Medical Genetics, Umm-Al-Qura University, Makkah, Saudi Arabia.
Introduction: It is well established that the PKHD1 mutations are associated with autosomal recessive polycystic kidney disease (ARPKD). Although, PKHD1 mutations are also detected in certain cancer types, to our knowledge in rare tumors such as, atypical teratoid rhabdoid tumor (ATRT), primary neuro-ectodermal tumor (PNET), atypicalchoroid plexus papilloma (a-CPP), amelanotic ano-rectal melanoma (AMM), and breast phyllodes tumors PKHD1 mutations profiling is not reported.
Methods: In order to determine the PKHD1 gene mutation patterns in the brain, rectal, and breast tumors we have analyzed these tumor DNA by Ion Proton Next generation DNA sequencing.
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