KMT2A-MLLT3 AML Masquerading as JMML may Disguise Fatal Leukemia.

Oman Med J

Pediatric Hematology, Oncology and HSCT Unit, Department of Child Health, Sultan Qaboos University Hospital, Muscat, Oman.

Published: November 2019

We present a mortality case showcasing t(9;11)-positive acute myeloid leukemia/juvenile myelomonocytic leukemia (AML/JMML) overlap to shed light on this lethal molecular subtype of AML. In this case, the flawed assumption that JMML was to blame impeded the prompt undertaking of appropriate treatment for AML in our 14-month-old patient. This article aims to scrutinize the catastrophic sequel of such an overlap in leukemia and refutes the contemporary diagnostic methods.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851066PMC
http://dx.doi.org/10.5001/omj.2019.99DOI Listing

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