AI Article Synopsis
- The case study discusses an 11-year-old girl diagnosed with Mixed Connective Tissue Disease (MCTD) that initially showed symptoms of Idiopathic Dermatomyositis (IDM).
- The disease later progressed to include symptoms associated with Juvenile Rheumatoid Arthritis (JRA) and Sjögren's Syndrome (SS), along with specific serum antibodies (anti-RNP), but lacking others (anti-dsDNA and anti-Sm).
- The authors highlight that MCTD in children is very rare and that the prognosis largely depends on the potential impact on kidney or blood functions.
Article Abstract
The Authors report a case of MCTD in a 11 years old girl. Initially the disease presented the classical clinical picture of IDM. Successively its evolution was marked by the appearance of the typical clinical features of JRA, SS and of serum antibodies anti-RNP and by absence of antibodies anti-dsDNA and anti-Sm. These data are characteristic of MCTD. The occurrence of this disease in children is extremely rare and the prognosis is related to a possible renal and/or haemopoietic involvement.
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