Long-term growth management can be challenging for patients, families and healthcare professionals (HCP). Personalised optimal responses to growth hormone (GH) therapy depend on the creation of a good working relationship between the patient and family and the HCPs responsible for care. Current unmet needs in growth management will be discussed, focusing on the likelihood of a poor growth response and its identification and management with emphasis on the importance of good adherence to GH therapy. Digital tools are now available to record injections and communicate accurate adherence data to the HCP and patient. Psychological barriers to good adherence will be covered, with techniques identified to change behaviour and improve outcome. Motivational interviewing is a valuable skill in this respect and should be taught to both medical and nursing HCPs to enhance the quality of the relationship with the patient and family. Key messages are, firstly, the importance of personalised care with the HCP using acquired psychological skills to prevent and manage poor adherence. Secondly, a human-eHealth partnership is necessary to maximise the benefit of new digital tools to aid in successful growth management.
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http://dx.doi.org/10.4274/jcrpe.galenos.2019.2019.0153 | DOI Listing |
Mol Pharm
March 2025
Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Positive surgical margins following radical prostatectomy significantly contribute to tumor recurrence. While systemic chemotherapy demonstrates limited efficacy in this context, local chemotherapy drug delivery systems based on nanomaterials offer promising strategies to address this issue by modifying drug release kinetics and distribution, thereby enhancing antitumor effects while minimizing the toxicities associated with systemic chemotherapy. In this study, we utilized electrospun nanofibrous mats loaded with docetaxel for sustained drug delivery.
View Article and Find Full Text PDFAm J Public Health
April 2025
Morgan McDonald is the National Director for Population Health and Health Equity Leadership at the Milbank Memorial Fund, New York, NY.
Directing depolarization efforts toward those with authority over public health funding and population health policies has great potential to improve health outcomes. Two nonpartisan legislative and executive branch state leadership programs demonstrated personal growth and mutual respect among participants necessary for depolarization that was evidenced by cross-state and cross-party policy implementation. Intentional cohort selection of politically and demographically diverse participants, ground rules based on fundamental values, and curriculum emphasizing collective problem-solving built trust and curiosity despite differing viewpoints.
View Article and Find Full Text PDFEur J Cardiothorac Surg
March 2025
Department of Cardiothoracic Surgery, Radboud University Medical Center, Nijmegen, Netherlands.
Objectives: This study evaluates a staged selective hybrid approach for acute type A aortic dissection. The approach involves a zone 2 aortic arch replacement with debranching of the brachiocephalic trunk and left common carotid artery to create a landing zone for thoracic endovascular aortic repair. This repair is performed either preemptively in the subacute phase to promote remodelling or electively in the chronic phase to manage aneurysm formation.
View Article and Find Full Text PDFPLoS One
March 2025
College of Economics and Management, Shenyang Agricultural University, Shenyang, Liaoning, China.
How does swine insurance affect the swine production efficiency in China? We focus on micro-survey data from 582 swine farmers in Liaoning Province, and uses the propensity score matching method (PSM) and mediated effects model for the empirical examination. The results indicate that swine insurance positively impacts production efficiency, compared to uninsured farmers, those who participate in swine insurance exhibit a 4.7% improvement in production efficiency.
View Article and Find Full Text PDFJ Hosp Palliat Nurs
March 2025
Assisted living (AL) and residential care (RC) settings are experiencing substantial growth as older adults with lower care needs seek alternatives to nursing homes. Despite this trend, there is a lack of skilled nursing care to support palliative care (PC) in these environments. Primary PC delivered by AL staff has emerged as a potential model to bridge this gap, focusing on symptom management and holistic support for individuals with serious illness.
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