We detected a highly pathogenic avian influenza A(H5N8) virus in lung samples of 2 gray seals (Halichoerus grypus) stranded on the Baltic coast of Poland in 2016 and 2017. This virus, clade 2.3.4.4 B, was closely related to avian H5N8 viruses circulating in Europe at the time.
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http://dx.doi.org/10.3201/eid2512.181472 | DOI Listing |
Cancers (Basel)
December 2024
Department of Biology, Howard University, Washington, DC 20059, USA.
Somatic and genetic mutations in glutathione peroxidases (GPxs), including GPx7 and GPx8, have been linked to intellectual disability, microcephaly, and various tumors. GPx7 and GPx8 evolved the latest among the GPx enzymes and are present in the endoplasmic reticulum. Although lacking a glutathione binding domain, GPx7 and GPx8 possess peroxidase activity that helps the body respond to cellular stress.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Yantai Key Laboratory of Characteristic Agricultural Biological Resources Conservation and Germplasm Innovative Utilization, College of Life Sciences, Yantai University, Yantai 264005, China.
Powdery mildew, caused by f. sp. (), is a disease that seriously harms wheat production and occurs in all wheat-producing areas around the world.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Key Laboratory for Forest Genetics and Tree Improvement and Propagation in University of Yunnan Province, Southwest Forestry University, Kunming 650224, China.
Plant protease inhibitors are a ubiquitous feature of plant species and exert a substantial influence on plant stress responses. However, the (Kunitz trypsin inhibitor) family responding to abiotic stress has not been fully characterized in . In this study, we conducted a genome-wide study of the family and analyzed their gene structure, gene duplication, conserved motifs, cis-acting elements, and response to stress treatment.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Key Laboratory of Veterinary Medicine in Universities of Sichuan Province, College of Animal Husbandry and Veterinary Medicine, Southwest Minzu University, 16 Yihuan Rd., Chengdu 610041, China.
Canine distemper (CD) is a highly infectious disease of dogs which is caused by canine distemper virus (CDV). Previous studies have demonstrated that CDV infection can induce autophagy in cells. However, the mechanism underlying CDV-induced autophagy remains not fully understood.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Department of Virology, Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26, Georgi Bonchev Str., 1113 Sofia, Bulgaria.
Herpes viruses are highly contagious agents affecting all classes of vertebrates, thus causing serious health, social, and economic losses. Within the One Health concept, novel therapeutics are extensively studied for both veterinary and human control and management of the infection, but the optimal strategy has not been invented yet. Lactic acid bacteria are key components of the microbiome that are known to play a protective role against pathogens as one of the proposed mechanisms involves compounds released from their metabolic activity.
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