Laryngeal leiomyosarcoma is a rare smooth muscle malignancy of the head and neck region. Diagnosis is based on immunohistochemistry. Here we present a case of laryngeal leiomyosarcoma that was diagnosed and treated in our center, focusing on the clinical features, histological diagnosis and management of this rare disease.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848582 | PMC |
| http://dx.doi.org/10.1007/s12070-018-1553-7 | DOI Listing |
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Article Synopsis
- The study focused on the clinical features, treatment options, and prognosis of laryngeal leiomyosarcoma (LLMS), particularly looking at cases associated with Epstein-Barr virus (EBV) and HIV infections.
- It reported on a specific case of EBV-associated LLMS in an adult HIV patient and reviewed existing literature, finding that only 62 cases have been documented.
- The findings showed that LLMS has a 5-year survival rate of 64%, while EBV association seems to negatively impact survival rates, with EBV-positive patients showing a lower rate of 50%.
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