Objectives: To assess the reliability, validity, and sensitivity of a novel device (Notio Konect™) which is purported to provide a real-time analysis of aerodynamic drag area (CdA) during cycling.
Design: Observational, cross-sectional study.
Methods: Fifteen trained cyclists rode in an indoor velodrome using three different positions (upright, aero [holding aero bars], and optimized aero [similar to aero, but wearing a time-trial helmet]). They completed six 1-min trials in each position. The CdA was measured with Notio and with two other systems (Track Aero System™ [TAS] and a validated mathematical model).
Results: The CdA measured with Notio showed good reliability (intra-class correlation coefficient [ICC]=0.92, 90% confidence interval [CI]=0.89-0.95). Notio showed an almost perfect relationship with both TAS (ICC=0.99, 90% CI=0.98-0.99) and the mathematical model (ICC=0.99, 90% CI=0.98-0.99). However, the CdA values provided by the former (0.308±0.051m) were significantly higher (albeit with a trivial effect size [ES]) compared with TAS (0.300±0.051m, p<0.001, ES=0.15) and the mathematical model (0.303±0.051m, p=0.005, ES=0.09). The CdA was higher in the upright than in the aero position with all systems (all p<0.001, ES=1.84-1.89), and higher in the aero than in the optimized aero position when measured with TAS (p=0.033, ES=0.22) or the mathematical model (p=0.024, ES=0.24), but not with Notio (p=0.220, ES=0.19).
Conclusions: Notio appears to be reliable, strongly correlated to other established systems, and discerns large (upright vs aero) but not small (aero vs optimized aero) variations in riding position. Further research is needed to confirm its validity in outdoor conditions.
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http://dx.doi.org/10.1016/j.jsams.2019.10.023 | DOI Listing |
BMC Health Serv Res
January 2025
Department of Engineering, University Campus Bio-Medico of Rome, Via Alvaro del Portillo 21, Rome, 00128, Italy.
Background: Oxygen therapy is critical and vital treatment for hypoxemia and respiratory distress, however, access to reliable oxygen systems remains limited in SSA. Despite WHO initiatives that distributed over 30,000 OC oxygen concentrators worldwide, SSA faces significant challenges related to their maintenance and use, due to harsh environmental conditions, technical skill shortages and inadequate infrastructure. This review aims to systematically identify and assess the literature on OC design adaptations, maintenance challenges, and knowledge gaps in SSA, providing actionable recommendations to inform innovative and context-sensitive solutions to improve healthcare delivery in the region.
View Article and Find Full Text PDFBMC Public Health
January 2025
Advanced Wellbeing Research Centre, Sheffield Hallam University, Sheffield, UK.
Background: Workplace health screening rarely includes measures of cardiorespiratory fitness, despite it being a greater predictor of cardiovascular disease and all-cause mortality than other routinely measured risk factors. This study aimed to determine the comparative acceptability of using a novel seismocardiography device to measure cardiorespiratory fitness via VO max during a workplace health check.
Methods: Participants were invited to participate in workplace health screening sessions where VO max was assessed by both seismocardiography at rest and sub-maximal exercise testing, in order for acceptability of both to be compared across multiple domains.
J Biol Eng
January 2025
AVT - Biochemical Engineering, RWTH Aachen University, Forckenbeckstr. 51, D-52074, Aachen, Germany.
Background: Shake flasks are essential tools in biotechnological development due to their cost efficiency and ease of use. However, a significant challenge is the miniaturization of process analytical tools to maximize information output from each cultivation. This study aimed to develop a respiration activity online measurement system via off-gas analysis, named "Transfer rate Online Measurement" (TOM), for determining the oxygen transfer rate (OTR), carbon dioxide transfer rate (CTR), and the respiration quotient (RQ) in surface-aerated bioreactors, primarily targeting shake flasks.
View Article and Find Full Text PDFMikrochim Acta
January 2025
School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang, 421001, China.
A ratiometric fluorescent nanoprobe (CDs-Rho), synthesized through the simple covalent amide linkage between carbon dots (CDs) and pH-sensitive rhodamine dye (Rho), was designed for the precise sensing and imaging of extremely alkaline environments. The sensing mechanism involves the opposite pH-dependent fluorescence changes in CDs and Rho, respectively, coupled with pH-regulated FRET efficiency from CDs to Rho. The nanoprobe features a wide pH response window from pH 7.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Communication Engineering, School of Electronics Engineering, Vellore Institute of Technology, Vellore, Tamil Nadu, India.
The design and characterisation of a novel dual-band implantable antenna with compact size is presented in this research. The antenna, which is [Formula: see text] in size and operates at two critical frequencies-0.954 GHz in the UHF band and 2.
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