Bistachybotrysin K (), one new phenylspirodrimane dimer with a central 6/7 oxygen heterocycle core, was isolated from the fungus CGMCC 3.5365. Its structure was elucidated by extensive spectroscopic data and single-crystal X-ray diffraction. Compound showed significant cytotoxicity against human tumor cell lines HCT116, NCI-H460, BGC823, Daoy, and HepG2 with IC values in the range of 1.1-4.7 µM.
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| http://dx.doi.org/10.1080/10286020.2019.1680645 | DOI Listing |
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