AI Article Synopsis

  • * A 25-year-old man with acute liver failure due to a sickle cell crisis showed positive results with NAC treatment.
  • * This case suggests that NAC might be a beneficial option for liver injuries linked to sickle cell disease.

Article Abstract

N-acetylcysteine (NAC) has been well studied in the treatment of acetaminophen-induced and select non-acetaminophen-induced liver failure. However, its role in the management of sickle cell hepatic crisis resulting in acute liver failure (ALF) is unknown. We describe and discuss the novel and beneficial use of NAC in a 25-year-old man with ALF due to sickle cell hepatic crisis. We further review ALF in sickle cell disease and NAC in the treatment of non-acetaminophen-induced liver failure. Our case highlights the promising role of NAC in sickle cell-related liver injury.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791608PMC
http://dx.doi.org/10.14309/crj.0000000000000161DOI Listing

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