Combinatorial Oxytocin Neuropharmacology in Social Cognition.

Trends Cogn Sci

Department of Psychology, Yale University, New Haven, CT, USA; Department of Neuroscience, Yale University School of Medicine, New Haven, CT, USA; Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT, USA. Electronic address:

Published: January 2020

The efficacy and reliability of using intranasal oxytocin (OT) to clinically enhance social functions remains undependable. We discuss the potential benefit of concurrent administration of OT and naloxone (NAL) to robustly modulate social behavior. We further suggest that combinatorial neuropharmacology approaches should exploit the interactions between OT and serotonin to regulate social functions.

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http://dx.doi.org/10.1016/j.tics.2019.10.004DOI Listing

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