miRNA-Microbiota Interaction in Gut Homeostasis and Colorectal Cancer.

Trends Cancer

Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA; Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA; Center for Microbiome Innovation, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address:

Published: November 2019

Gut homeostasis is maintained by dynamic host-microbiota interactions. Recently, miRNAs have emerged as key molecular regulators in the mediation of such interactions. Here, we discuss the role of a host miRNA-microbiome axis in gut homeostasis and colorectal cancer (CRC) and the involvement of diet and microbial metabolites in miRNA-mediated intestinal health.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480531PMC
http://dx.doi.org/10.1016/j.trecan.2019.08.003DOI Listing

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