AI Article Synopsis
- Cold agglutinins (CAs) are autoantibodies that can affect patients' responses during surgeries, particularly those involving cardio-pulmonary bypass.
- Ensuring that body temperature stays above the agglutination threshold is crucial for preventing complications during surgery.
- In a specific case during elective aortic valve replacement, the presence of CAs was noted, and the surgical team effectively managed it using normothermic bypass and warm blood cardioplegia.
Article Abstract
Cold agglutinins (CA) are autoantibodies whose clinical significance depends upon titer and thermal amplitude. Patients, which undergo cardio-pulmonary bypass and especially hypothermic cardioplegia myocardial protection, represent a challenge regarding operative management, as tissue temperature should be maintained above the threshold of agglutination. We report on a case in which the presence of CA was discovered during elective aortic valve replacement surgery, and managed with normothermic cardiopulmonary bypass and continuous retrograde warm blood cardioplegia administration.
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