Phytochemical studies on MeOH extract of stems of Euphorbia griffithii led to the isolation of one new hydrolyzable tannin dimer, corilagiffithiin (1) and one new galloyl-glucoside (2), alongside six known ones (3-8). Their structures and absolute configurations were determined by in depth spectroscopic analyses and comparison of their 1D NMR and MS data with literature reported values. Configurations of sugar moieties were determined by acidic hydrolysis and subsequent GC analysis of their corresponding trimethylsilylated L-cysteine adduct. At a concentration of 50 μM, compounds 1-3 showed no anti-inflammatory activities.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872693 | PMC |
| http://dx.doi.org/10.1007/s13659-019-00223-2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effective Use of DCM Root Extract Encapsulated by Thermosensitive Immunoliposomes for Targeted Drug Delivery in Prostate Cancer Cells.
Curr Issues Mol Biol
October 2024
Department of Pharmacology, University of the Free State, Bloemfontein 9300, South Africa.
Article Synopsis
- * Liposomes were created with a specific ratio of components and attached to a PSA antibody, successfully encapsulating anticancer drugs (doxorubicin and docetaxel) alongside plant extracts.
- * The study found that heating the liposomes to 39-40 °C activated them, releasing their contents and effectively inhibiting the growth of prostate cancer cell lines (LNCap and DU145) when compared to non-heated conditions.
An investigation of the pigments, antioxidants and free radical scavenging potential of twenty medicinal weeds found in the southern part of Bangladesh.
PeerJ
July 2024
Division of Soil Science, Bangladesh Wheat and Maize Research Institute, Dinajpur, Rangpur, Bangladesh.
Despite their overlooked status, weeds are increasingly recognized for their therapeutic value, aligning with historical reliance on plants for medicine and nutrition. This study investigates the medicinal potential of native weed species in Bangladesh, specifically pigments, antioxidants, and free radical scavenging abilities. Twenty different medicinal weed species were collected from the vicinity of Khulna Agricultural University and processed in the Crop Botany Department Laboratory.
View Article and Find Full Text PDFEuphorbia helioscopia L. exhibits promising therapeutic effects on hemangioendothelioma and melanoma through angiogenesis inhibition.
Phytomedicine
July 2024
Department of Biological Sciences, Faculty of Health Sciences, University of Macau, Macau, PR China; Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macau, PR China; Ministry of Education Frontiers Science Center for Precision Oncology, University of Macau, PR China; Proteomics, Metabolomics and Drug development core facility, Faculty of Health Sciences, University of Macau, Macau SAR, China. Electronic address:
Background: Euphorbia helioscopia L (EHL), a widely used medicinal plant in traditional Chinese medicine, has shown promising effects on certain cancers. However, previous studies on EHL did not elucidate the underlying molecular mechanisms. Herein, for the first time, we present the strong therapeutic potential of EHL extracts on malignant hemangioendothelioma, a rare type of vascular tumor.
View Article and Find Full Text PDFMicrofungi associated with dying in South Africa and their relative pathogenicity.
Fungal Syst Evol
November 2023
Department of Biochemistry, Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute (FABI), University of Pretoria, Private Bag X20, Hatfield, 0028, South Africa.
is a succulent shrub that is indigenous to South Africa and widely distributed throughout the country. Dying plants have been observed in their natural habitat in the Northern and Western Cape Provinces of South Africa in recent years. Stems displaying lesions were collected and the emerging cultures were identified based on ITS, LSU, , , and/or sequence data.
View Article and Find Full Text PDFComparative evaluation of antioxidant activity, total phenolic content, anti-inflammatory, and antibacterial potential of -derived functional products.
Front Pharmacol
February 2024
Laboratory of Biochemistry, Neurosciences, Natural Resources and Environment, Faculty of Sciences and Technologies, Hassan First University of Settat, Settat, Morocco.
This study assessed the medicinal properties of and (, known for their pharmaceutical benefits. Extracts from their flowers, stems, propolis, and honey were examined for phenolic content, antioxidant, anti-inflammatory, and antibacterial activities. Total phenolic content (TPC), total flavonoid content (TFC), and total condensed tannin (TCC) were determined using specific methods.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!