AI Article Synopsis
- The Chinese giant salamander is a cool animal that scientists study to understand how it lives a long time, survives without food, and breathes through its skin.
- Researchers found many special genes in this salamander and discovered that its immune system might have evolved quickly to help it adapt.
- They also learned that different parts of the salamander's skin have different jobs, like making mucus, fighting germs, and managing salt and water.
Article Abstract
The Chinese giant salamander Andrias davidianus is regarded as an ideal model for studying local adaptations, such as longevity, tolerance to starvation, and cutaneous respiration. Transcriptome analysis is useful for studying the large and complex genomes of amphibians. Based on the coding gene set of adult A. davidianus, dozens of A. davidianus-specific genes were identified and three signaling pathway (JAK-STAT, HIF-1, and FoxO) genes were expanded as compared with other amphibians. The results of the pathway analysis of A. davidianus-specific genes indicated that the molecular adaptation of A. davidianus may have required a more rapid evolution of the immune system. Additionally, for the first time, the gene expressions in different parts of the skin tissue were compared. The results of the comparison analysis demonstrated that lateral skin could be more focused on mucus secretion, dorsal skin on immunity and melanogenesis, and abdominal skin on water and salt metabolism. This study provides the first insight into studying longevity and starvation tolerance in A. davidianus, and offers a basis for further investigation of the molecular mechanisms of adaptations in amphibians.
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| http://dx.doi.org/10.1007/s00427-019-00641-9 | DOI Listing |
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