Objectives: Human progress is the satisfaction of human needs associated with life quality, social and economic justice. Considering that climate had significant effect on socio-economic behavior of Earth populations, the objective of this work was to evaluate the relationship between human progress and drought sensitivity behavior in Minas Gerais State, Brazil.
Methods: The human progress variable was generated by principal component analysis, considering the factors: Territorial occupation of the population, dependency ratio, urbanization degree, income, habitation, health, education, sanitation, security and human development index. The moisture index product was generated based on map algebra calculation in GIS, using WorldClim precipitation and MODIS evapotranspiration products. Nonlinear least squares method and Levenberg-Marquardt algorithm fit an exponential model to the moisture index (independent) and human progress (dependent) variables. Covariance and crossed-covariance functions were used to characterize the structure and magnitude of spatial dependence between the human progress and the moisture index co-variable.
Results: Couple modeling human progress and moisture index variability generated the human drought sensitivity behavior variable, representing the effects of regional climate in Homo sapiens population. The generated human drought sensitivity behavior values were inverted, i.e. lower and higher human drought sensitivity behavior values indicated higher and lower human sensitivity to drought, respectively. Adaptive management capacity with more capable governments combining economic and engineering solutions to maximize species, habitat, ecosystem survival and resilience, could generate best mitigation solutions to reduce potential impacts of climatic spatial variation in Minas Gerais state, Brazil.
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http://dx.doi.org/10.1016/j.scitotenv.2019.134966 | DOI Listing |
Am J Case Rep
December 2024
Department of Molecular Medicine and Surgery, Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden.
BACKGROUND Limb-girdle muscular dystrophy recessive 1 (LGMDR1) is an autosomal recessive degenerative muscle disorder characterized by progressive muscular weakness caused by pathogenic variants in the CAPN3 gene. Desmoplastic small round cell tumors (DSRCT) are ultra-rare and aggressive soft tissue sarcomas usually in the abdominal cavity, molecularly characterized by the presence of a EWSR1::WT1 fusion transcript. Mouse models of muscular dystrophy, including LGMDR1, present an increased risk of soft tissue sarcomas.
View Article and Find Full Text PDFIn Vitro Cell Dev Biol Anim
December 2024
Laboratorio de Líquido Sinovial, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra (INRLGII), Calzada México-Xochimilco No. 289, Col. Arenal de Guadalupe, 14389, Mexico City, Mexico.
Osteoarthritis (OA) is a chronic degenerative disease characterized by the progressive loss of articular cartilage. The role of cigarette smoke (CS) in OA is debated, with some studies suggesting a protective effect while others indicate it may pose a risk. Our preliminary findings suggest a link between smoking in young adults and severe knee OA, though the extent of this contribution is unclear.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Internal Medicine, Pusan National University School of Medicine, Busan, South Korea.
Proton pump inhibitors (PPIs) are among the most widely used drugs worldwide. However, their influence on the progression of end-stage kidney disease (ESKD) in established chronic kidney disease (CKD) cases is unclear. Using the Korean Health Insurance Review and Assessment database encoded by the Observational Medical Outcomes Partnership-Common Data Model (OMOP-CDM), patients with stage 3 or 4 CKD initiating PPIs or histamine-2 receptor antagonists (H2RAs) for over 90 days were enrolled from 2012 through 2021.
View Article and Find Full Text PDFSci Rep
December 2024
Division of Joint Surgery and Sports Medicine, Department of Orthopedic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Lines of evidence have indicated that type 2 diabetes mellitus (T2DM) is an independent risk factor for osteoarthritis (OA) progression. However, the study focused on the relationship between T2DM and OA at the transcriptional level remains empty. We downloaded OA- and T2DM-related bulk RNA-sequencing and single-cell RNA sequencing data from the Gene Expression Omnibus (GEO) dataset.
View Article and Find Full Text PDFSci Rep
December 2024
Health and Sports Medicine Department, Faculty of Sports Sciences and Health, University of Tehran, North Karegar St, P.O.B: 1439813117, Tehran, Iran.
Although the connection between muscular strength and flatfoot condition is well-established, the impact of corrective exercises on these muscles remains inadequately explored. This study aimed to assess the impact of intrinsic- versus extrinsic-first corrective exercise programs on muscle morphometry and navicular drop in boys with flexible flatfoot. Twenty-five boys aged 10-12 with flexible flatfoot participated, undergoing a 12-week corrective exercise program, with a shift in focus at six weeks.
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