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Does radiofrequency ablation of the lower oesophagus allow for clonal expansion of highly mutated neosquamous epithelium?
BMJ Oncol
October 2023
Department of Pathology, University of California San Francisco, San Francisco, California, USA.
Objective: In Barrett's oesophagus (BE), after radiofrequency ablation (RFA), the oesophagus can be repopulated with a stratified 'neosquamous epithelium' (NeoSE). While histologically normal, the origin and clonal make-up of this NeoSE is unknown. An increased understanding of NeoSE is important as some studies suggest that NeoSE is biologically abnormal.
View Article and Find Full Text PDFHypoxia and hypotension following industrial-grade anhydrous ethanol ablation of the vein of Marshall in the treatment of atrial fibrillation: a case report.
Pan Afr Med J
January 2025
Cardiovascular Department, The Affiliated People´s Hospital of Ningbo University, Ningbo, 315000, ZheJia, China.
This case presents a patient who experienced hypoxia and hypotension following the infusion of industrial-grade anhydrous ethanol into the vein of Marshall (VOM) during atrial fibrillation radiofrequency ablation. The hypotension lasted for at least three days, requiring dopamine support, while hypoxia persisted for over a week. The prolonged nature of these symptoms posed a diagnostic challenge.
View Article and Find Full Text PDFObjectives: Endoscopic ultrasonography (EUS)-guided radiofrequency ablation has recently been introduced as one of the management strategies for small pancreatic neuroendocrine neoplasms (PNENs). However, prospective data on its safety and efficacy remain limited.
Methods: This prospective pilot study was conducted at Okayama University Hospital from May 2023 to December 2024.
CT-Guided C2 Diagnostic Related Group Injection and Radiofrequency Ablation for Cervicogenic Headache.
AJNR Am J Neuroradiol
January 2025
From the Department of Radiology and Imaging, Hospital for Special Surgery, New York, New York
CT-guided injection and radiofrequency ablation (RFA) of the C2 dorsal root ganglion (DRG) is a safe and effective treatment for cervicogenic headache arising from C1-C2 joint arthritis. The C2 nerve root is unique in that it lacks a motor component; RFA can be performed with pain relief in exchange for occipital numbness. This video article outlines the imaging anatomy and technical considerations of this procedure.
View Article and Find Full Text PDFUltrasonic-Controlled Drug Release Prevents Protumorigenic Transition and Improves Sequential Targeting Effect to Enhance Treatment of Residual Hepatocellular Carcinoma.
Biomater Res
January 2025
Department of Ultrasound, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong Province 519000, China.
Insufficient radio-frequency ablation (IRFA) of hepatocellular carcinoma accelerates the recurrence of residual tumor, leading to a poor prognosis. Neutrophils (NEs), as the initial leukocytes to infiltrate the IRFA-associated inflammatory area, were utilized as drug carriers due to their inherent chemotactic properties for targeted delivery of chemotherapy drugs to the inflammatory site where residual tumor persists post-IRFA. Previous research has highlighted that the immunosuppressive cytokines in the tumor microenvironment could promote the transition of NEs into a protumorigenic phenotype.
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