We report a room temperature (RT) operation of a Fe:CdTe laser pumped by a Q-switched 2.94 μm Er:YAl(AlO) laser. The Fe:CdTe laser produced 2 mJ of output energy at λ=5.55 μm with slope efficiency of 16% with respect to absorbed pump energy. With the use of an intracavity prism, the spectral tuning was demonstrated in the 5.1-6.3 μm range, being the longest wavelength tuning achieved for Fe:II-VI lasers. The lifetime of the upper laser level was measured to be 530 ns at RT.
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http://dx.doi.org/10.1364/OL.44.005453 | DOI Listing |
J Integr Neurosci
January 2025
Neuroscience Department, University of Connecticut Health, School of Medicine, Institute for Systems Genomics, Farmington, CT 06030, USA.
Background: In neuroscience, Ca imaging is a prevalent technique used to infer neuronal electrical activity, often relying on optical signals recorded at low sampling rates (3 to 30 Hz) across multiple neurons simultaneously. This study investigated whether increasing the sampling rate preserves critical information that may be missed at slower acquisition speeds.
Methods: Primary neuronal cultures were prepared from the cortex of newborn pups.
Pharmaceutics
December 2024
Department of Periodontal Diseases and Oral Mucosa Diseases, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.
Oral candidiasis, predominantly caused by , presents significant challenges in treatment due to increasing antifungal resistance and biofilm formation. Antimicrobial photodynamic therapy (aPDT) using natural photosensitizers like riboflavin and hypericin offers a potential alternative to conventional antifungal therapies. : A systematic review was conducted to evaluate the efficacy of riboflavin- and hypericin-mediated aPDT in reducing Candida infections.
View Article and Find Full Text PDFPharmaceutics
December 2024
Department of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia.
Background/objectives: Selective laser sintering (SLS) is one of the most promising 3D printing techniques for pharmaceutical applications as it offers numerous advantages, such as suitability to work with already approved pharmaceutical excipients, the elimination of solvents, and the ability to produce fast-dissolving, porous dosage forms with high drug loading. When the powder mixture is exposed to elevated temperatures during SLS printing, the active ingredients can be converted from the crystalline to the amorphous state, which can be used as a strategy to improve the dissolution rate and bioavailability of poorly soluble drugs. This study investigates the potential application of SLS 3D printing for the fabrication of tablets containing the poorly soluble drug carvedilol with the aim of improving the dissolution rate of the drug by forming an amorphous form through the printing process.
View Article and Find Full Text PDFPlants (Basel)
January 2025
Intelligent Equipment Research Center, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China.
Precision pesticide application mainly relies on canopy volume, resulting in varied application effectiveness across different density areas of orchard trees. This study examined pesticide application effectiveness based on the spray wind, canopy volume, and leaf area within the canopy, providing variable bases for precise regulation of spray wind and pesticide dosage. The study addresses the knowledge gap by utilizing laser detection and ranging (LiDAR) to measure the thickness and leaf area of orchard tree canopies.
View Article and Find Full Text PDFPolymers (Basel)
January 2025
School of Materials Science and Engineering, Ocean University of China, Qingdao 266100, China.
In organic solar cells, the aggregation and crystallization of polymers are significant for bulk heterojunction. Blending with acceptor materials, polymer donor materials can adjust their aggregation by the movement of the chain segments. In this paper, the unfused structures based on thiophene and carbazole are respectively designed and introduced into the donor-acceptor copolymer donor materials to investigate the influence of flexible and rigid structures on polymer-aggregation leading photoelectric performance.
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