AI Article Synopsis
- The study examined the link between serum bilirubin levels and fragmented QRS (fQRS) in patients with acute coronary syndrome, involving 736 participants.
- The fQRS (+) group showed significantly lower left ventricular ejection fraction and total bilirubin levels compared to the control group, indicating potential cardiac dysfunction.
- Over a 1-year follow-up, the fQRS (+) group experienced more adverse events, suggesting that higher bilirubin levels could predict fQRS formation and related complications in these patients.
Article Abstract
To assess the relationship between serum bilirubin levels and fragmented QRS (fQRS), and their association with adverse events in patients with acute coronary syndrome. This study included a total of 736 patients. Laboratory results such as bilirubin levels, renal and liver function tests were obtained from the first available blood sample. Left ventricular ejection fraction, end-diastolic diameter and total bilirubin level were significantly lower in fQRS (+) group than in the control group (45.0 [40.0-55.0] vs 50.0 [45.0-60.0]%; p < 0.001; 4.7 [4.6-5.1] vs 4.7 [4.5-4.9] cm; p < 0.001; 0.66 [0.49-5.1] vs 0.72 [0.53-0.97] md/dl; p = 0.017); respectively. Occurrence of adverse events was significantly higher in fQRS (+) group (32.5 vs 20.5 %; p = 0.013) during mean 1-year follow-up period. Total bilirubin level is an independent predictor of fQRS formation, which is associated with the presence of adverse events in patients with acute coronary syndrome.
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| http://dx.doi.org/10.2217/bmm-2018-0493 | DOI Listing |
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