Time-dependent change in pain threshold following neurolytic celiac plexus block.

Pain Manag

Department of Anesthesiology & Critical Care Medicine, Division of Pain Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Published: November 2019

AI Article Synopsis

  • - The study investigates how ethanol affects pain recurrence in patients who underwent a nerve block procedure (NCPB) for pain relief.
  • - 31 patients were monitored, showing an average immediate pain score reduction of 83.8% after the procedure, with 73% experiencing a sustained decrease of 50-66% after 80-100 days.
  • - On average, pain returned to pre-procedure levels approximately 103 days post-NCPB, indicating the temporary effectiveness of ethanol for pain management.

Article Abstract

To determine the long-term effect of ethanol relative to the re-occurrence of pain in postneurolytic celiac plexus block (NCPB) patients. A noninterventional study on 31 patients who had undergone NCPB to illustrate the average change of pain score over time. All NCPB patients reported a pain score decrease of 83.8% right after the procedure. 73% of patients reported 50-66% decrease in pain 80-100 days postprocedure. The temporal threshold for the return of pain scores to average preblock level was determined to be 103 post-NCPB procedure days. In this study, NCPB patients demonstrate return of pain to baseline subsequent to the analgesic effects of ethanol after a mean 103 days.

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Source
http://dx.doi.org/10.2217/pmt-2019-0021DOI Listing

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