The actinomycete strain FIM06-0036 was isolated from marine sponge sample collected from the East China Sea and identified as sp. based upon the results of 16S rRNA sequence analysis. One new alkaloid, 2-ethylhexyl 1H-imidazole-4-carboxylate (), together with a known alkaloid butyl 1H-imidazole-4-carboxylate () was obtained from the fermentation products of this strain, the structures of compounds and were determined by their detailed analysis of 1 D, 2 D NMR and HR-ESI-MS data, along with literature data analysis. Compounds and were evaluated for their antimicrobial activity with MIC (minimum inhibitory concentration) values ranging from 8 to 256 μg · mL against
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