AI Article Synopsis
- * Most of the markers met Hardy-Weinberg Equilibrium expectations, and no significant deviations in linkage disequilibrium were found, indicating reliability.
- * The DIPplex kit demonstrated a very high power of discrimination and a low match probability, making it a valuable tool for individual identification and paternity testing in challenging cases in Kuwait.
Article Abstract
This study evaluates the forensic utility of the 30 insertion and deletion (indel) markers contained in the Qiagen Investigator® DIPplex kit in the Kuwaiti population (n = 150). All but one of the 30 markers were shown to conform to the expectations of the Hardy-Weinberg Equilibrium. Linkage disequilibrium tests showed no statistically significant deviation from independence. The high combined power of discrimination (CPD > 99.999%) and low combined match probability (CMP) of 2.736 × 10 provide a satisfactory level of discrimination, allowing the DIPplex loci to be used as forensic markers for individual identification in Kuwait. The paternity indices indicate the usefulness of the DIPplex kit as a supplementary typing system for challenging paternity cases in Kuwait.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181444 | PMC |
| http://dx.doi.org/10.1007/s00414-019-02180-4 | DOI Listing |
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