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Mathematical assessment of the role of temperature on desert locust population dynamics.
PLoS One
January 2025
School of Mathematics and Statistics, College of Science, Rochester Institute of Technology, Rochester, New York, United States of America.
This study presents a novel non-autonomous mathematical model to explore the intricate relationship between temperature and desert locust population dynamics, considering the influence of both solitarious and gregarious phases across all life stages. The model incorporates temperature-dependent parameters for key biological processes, including egg development, hopper growth, adult maturation, and reproduction. Theoretical analysis reveals the model's capacity for complex dynamical behaviors, such as multiple stable states and backward bifurcations, suggesting the potential for sudden and unpredictable population shifts.
View Article and Find Full Text PDFPre-operative subjective functional capacity and postoperative outcomes in adult non-cardiac surgery: a systematic review and meta-analysis.
Anaesthesia
January 2025
Department of Anaesthesiology, Institute of Science Tokyo Hospital, Bunkyo, Tokyo, Japan.
Introduction: Assessment of functional capacity is an essential part of peri-operative risk stratification. Subjective functional capacity is easier to examine than objective tests of patient fitness. However, the association between subjective functional capacity and postoperative outcomes has not been established.
View Article and Find Full Text PDFBridging the gap: An outlook of oncofertility care in Africa.
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Department of Obstetrics and Gynecology, Aga-Khan University, Nairobi, Kenya.
This article examines existing literature on oncofertility in Africa and explores the barriers to oncofertility care. Patient-level barriers include lack of awareness about fertility preservation options, financial constraints, and the heavy emotional burden of cancer diagnosis and treatment. Healthcare-provider barriers encompass lack of awareness, prioritization of prompt cancer treatment, and implicit biases.
View Article and Find Full Text PDFLactate-enhanced-qSOFA (LqSOFA) score as a predictor of in-hospital mortality in patients with sepsis: systematic review and meta-analysis.
Eur J Trauma Emerg Surg
January 2025
Facultad de Medicina Humana, Universidad Privada Antenor Orrego, Trujillo, Perú.
Introduction: Sepsis is a systemic process that refers to a deregulated immune response of the host against an infectious agent, involving multiple organ dysfunction. It is rapidly progressive and has a dismal prognosis, with high mortality rates. For this reason, it is necessary to have a tool for early recognition of these patients, with the aim of treating them appropriately in a timely manner.
View Article and Find Full Text PDFSafety, Tolerability, and Immunogenicity of the Invaplex Vaccine Co-Administered with the dmLT Adjuvant in Dutch and Zambian Adults: Study Protocol for a Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Phase Ia/b Clinical Trial.
Vaccines (Basel)
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Leiden University Center for Infectious Diseases, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Background: Shigella infections remain endemic in places with poor sanitation and are a leading cause of diarrheal mortality globally, as well as a major contributor to gut enteropathy and stunting. There are currently no licensed vaccines for shigellosis but it has been estimated that an effective vaccine could avert 590,000 deaths over a 20-year period. A challenge to effective Shigella vaccine development has been the low immunogenicity and protective efficacy of candidate Shigella vaccines in infants and young children.
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