This article describes methods used to combine into a common scale resource-based relative values from separate specialties. The key to producing a common scale is identifying pairs ("links") of services from different specialties that require approximately equal amounts of intraservice work. We distinguished two kinds of pairs of link services, those judged to be the same and those judged to be equivalent, usually within a narrow category of medical activity. Working with a cross-specialty panel of physicians and with data on time factors from a national survey, we selected sufficient links to connect each specialty to others by at least four links. We then used the weighted least-squares method to locate all the links optimally on a single, common scale. Analyses of the accuracy of this scale showed that the typical disagreement between specialties about where to locate the intraservice work of a given service was only 7%. Other analyses showed that the accuracy of the common scale was not sensitive to different classes of links.
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An Bras Dermatol
March 2025
Department of Dermatology, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil. Electronic address:
Background: Chronic pruritus is the defining symptom of atopic dermatitis (AD). Although AD is common in Latin America, there is little data regarding pruritus intensity, characteristics, and effects on quality of life in this population.
Objective: This cross-sectional study aimed to evaluate pruritus in 91 patients with AD at a tertiary university hospital in São Paulo, Brazil.
Background: Oral language skills are a critical foundation for education and psychosocial development. Learning to read, in particular, depends heavily on oral language skills. The Nuffield Early Language Intervention (NELI) has been shown to improve the language of 4-5-year-old children entering school with language weaknesses in four robust trials.
View Article and Find Full Text PDFIntroduction: Controlled Oral Word Association Test (COWAT) is a common neuropsychological assessment tool used to evaluate an individual's semantic and phonemic verbal fluency. The defining feature of this test is the imposed time limit (typically 60 s per task) and the initial letter constraints. Evaluating the performance on COWAT has been challenging, because numerous factors may complicate the interpretation of the obtained results.
View Article and Find Full Text PDFPerfluoroalkyl substances (PFAS) represent a broad group of synthetic chemicals that have raised concerns related to their long-term environmental persistence and potential health risks. Although several efforts have been dedicated to establishing international restrictions on their use, the definition of what qualifies as a PFAS remains a matter of debate among scientists, regulatory agencies, and industry. This article provides a brief overview of the different approaches proposed and adopted to date for identifying and grouping of these pollutants, either based on common structural motifs or on the combination of multiple factors, including functional uses, degradation behavior, physicochemical properties, and toxicity.
View Article and Find Full Text PDFBiochem Genet
March 2025
Department of Medical Biology, Faculty of Medicine, Yeditepe University, Istanbul, Turkey.
Multiple sclerosis (MS) is among the most common autoimmune disorders and is characterized by inflammation and degeneration affecting the central nervous system. Glatiramer acetate (GA) is an immunomodulatory drug utilized for treating relapsing-remitting MS. However, a considerable number of patients do not exhibit an appropriate response to this drug.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!