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http://dx.doi.org/10.5826/dpc.0904a12DOI Listing

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Article Synopsis
  • Pilomatricoma (PM) is a benign skin tumor that originates from the hair matrix, typically appearing as a hard nodule on normal skin, making early detection difficult.
  • A study analyzed six cases of bullous PM in primarily adolescent Chinese patients, noting a higher prevalence in females and a correlation between lesion location and vaccination sites.
  • The findings highlight the distinct dermatoscopic features and histological characteristics of bullous PM, suggesting that dermatoscopy can serve as a quick and effective diagnostic tool.
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To determine the prevalence of anatomical variations of nasal cavity and paranasal sinuses of patients with chronic rhinosinusitis (CRS) on CT scan imaging. To correlate the Anatomical variations with the extent of CRS. 100 patients attending the ENT outpatient department with clinically diagnosed CRS were selected for study based on inclusion and exclusion criteria.

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Symptomatic unilateral idiopathic giant bullous emphysema : a case report.

BMC Pulm Med

September 2022

Department of Respiratory Medicine, Connolly Hospital, Blanchardstown, Dublin 15, Ireland.

Background: Idiopathic Giant Bullous Emphysema (or Vanishing Lung Syndrome) is a rare condition which is usually associated with male gender, active smoking and underlying emphysematous disease. We present an unusual case of a giant bulla occurring in the absence of these risk factors.

Case Presentation: A 54-year-old woman presented to the respiratory outpatient clinic with gradually worsening left sided chest discomfort, which was most marked during a recent flight.

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Bullous Pilomatricoma After Influenza Vaccination.

Clin Cosmet Investig Dermatol

April 2022

Department of Dermatology, Peking University People's Hospital, Beijing, 100044, People's Republic of China.

Pilomatricoma, also known as "benign calcifying epithelioma", is an uncommon slow-growing benign adnexal skin tumor, which originates from primitive cells of the hair matrix and usually appears as a solitary, firm, and asymptomatic nodule beneath the skin. Bullous pilomatricoma is a rare form of pilomatricoma, always presenting with firm subcutaneous nodules with a bullous appearance. In this study, we report a 9-year-old Chinese presenting girl with bullous pilomatricoma after influenza vaccination.

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We studied CD34+ stromal cells/telocytes (CD34+SCs/TCs) in pathologic skin, after briefly examining them in normal conditions. We confirm previous studies by other authors in the normal dermis regarding CD34+SC/TC characteristics and distribution around vessels, nerves and cutaneous annexes, highlighting their practical absence in the papillary dermis and presence in the bulge region of perifollicular groups of very small CD34+ stromal cells. In non-tumoral skin pathology, we studied examples of the principal histologic patterns in which CD34+SCs/TCs have (1) a fundamental pathophysiological role, including (a) fibrosing/sclerosing diseases, such as systemic sclerosis, with loss of CD34+SCs/TCs and presence of stromal cells co-expressing CD34 and αSMA, and (b) metabolic degenerative processes, including basophilic degeneration of collagen, with stromal cells/telocytes in close association with degenerative fibrils, and cutaneous myxoid cysts with spindle-shaped, stellate and bulky vacuolated CD34+ stromal cells, and (2) a secondary reactive role, encompassing dermatitis-e.

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