Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.4049/jimmunol.1901268 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Author Correction: IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting.
Nat Commun
December 2024
Cancer Immunology Program, Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne, 3002, Victoria, Australia.
Author Correction: Neoantigen-specific stem cell memory-like CD4 T cells mediate CD8 T cell-dependent immunotherapy of MHC class II-negative solid tumors.
Nat Immunol
August 2023
Division of Developmental Immunology, La Jolla Institute for Immunology, La Jolla, CA, USA.
Remodeling Tumor Immunogenicity with Dual-Activatable Binary CRISPR Nanomedicine for Cancer Immunotherapy.
ACS Nano
March 2023
Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Key Laboratory of Anti-Inflammatory of Immune Medicines of Ministry of Education, Anhui Institute of Innovative Drugs, The Second Affiliated Hospital of Anhui Medical University, School of Pharmacy, Anhui Medical University, Hefei 230032, China.
The specific recognition of cancer cells by the body's immune system is an essential step in initiating antitumor immunity. However, the decreased expression of major histocompatibility complex class I (MHC-1) and overexpression of programmed death ligand 1 (PD-L1) causes insufficient tumor-associated antigens presentation and inactivation of T cells, which accounts for poor immunogenicity. To remodel tumor immunogenicity, herein, a dual-activatable binary CRISPR nanomedicine (DBCN) that can efficiently deliver a CRISPR system into tumor tissues and specifically control its activation is reported.
View Article and Find Full Text PDFCorrection to: TIGIT blockade enhances tumor response to radiotherapy via a CD103 + dendritic cell-dependent mechanism.
Cancer Immunol Immunother
May 2023
Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
A glia cell dependent mechanism at a peripheral nerve plexus critical for target-selective axon regeneration.
bioRxiv
January 2023
Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
A critical step for functional recovery from peripheral nerve injury is for regenerating axons to connect with their pre-injury targets. Reestablishing pre-injury target specificity is particularly challenging for limb-innervating axons as they encounter a plexus, a network where peripheral nerves converge, axons from different nerves intermingle, and then re-sort into target-specific bundles. Here, we examine this process at a plexus located at the base of the zebrafish pectoral fin, equivalent to tetrapod forelimbs.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!