Anterior open bite (AOB) is characterized by the lack of overlap or contact between maxillary and mandibular incisors, while the posterior teeth are in occlusion. Correction of this malocclusion is challenging due to difficulties in determining and addressing the etiologic factors, and the high relapse rate. A multidisciplinary approach may be necessary, with participation of Orthodontics, Surgery and Speech Therapy, to achieve adequate esthetic and functional results for long term stability. The present paper discusses the treatment options for AOB, their advantages and implications.
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http://dx.doi.org/10.1590/2177-6709.24.5.069-078.bbo | DOI Listing |
Lancet Microbe
January 2025
Jenner Institute, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.
Background: R21 is a novel malaria vaccine, composed of a fusion protein of the malaria circumsporozoite protein and hepatitis B surface antigen. Following favourable safety and immunogenicity in a phase 1 study, we aimed to assess the efficacy of R21 administered with Matrix-M (R21/MM) against clinical malaria in adults from the UK who were malaria naive in a controlled human malaria infection study.
Methods: In this open-label, partially blinded, phase 1-2A controlled human malaria infection study undertaken in Oxford, Southampton, and London, UK, we tested five novel vaccination regimens of R21/MM.
Cureus
December 2024
Plastic Surgery, West Virginia University School of Medicine, Morgantown, USA.
Despite frequent occurrences, especially throughout the Appalachian region, fish bite injuries remain largely underreported. Muskellunge anglers are at a particularly heightened risk due to the fish's large mouth and notably sharp teeth. We present a case of a male who sustained an injury to the right volar thumb following a muskellunge bite.
View Article and Find Full Text PDFJ Clin Orthod
November 2024
Division of Orthodontics, Department of Craniofacial Sciences; Division of Orthodontics, University of Connecticut School of Dental Medicine, Farmington, CT.
Cureus
December 2024
Internal Medicine, AdventHealth Orlando, Orlando, USA.
spp. rarely cause infection in humans and are most common in the immunocompromised population. Pulmonary nocardiosis is the most common presentation.
View Article and Find Full Text PDFJ Craniofac Surg
January 2025
Division of Plastic Surgery, Department of Surgery, Dalhousie University.
Introduction: Macroglossia is a frequent clinical feature of Beckwith-Wiedemann syndrome (BWS), a congenital overgrowth disorder. Macroglossia can lead to abnormal breathing, feeding, speech, and dentoskeletal development. Partial glossectomy is a common intervention aimed at reducing these abnormalities.
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