Centric relation (CR) is one of the core research contents in orthodontics, prosthodontics, and gnathology, acting as an important physiological factor in reconstructing the occlusion and adjusting the occlusal relationship. For over a century, CR is still a controversial subject in dentistry. CR has been redefined for several times, and recently, its application has been widened in orthodontics, including orthodontic diagnosis, clinical examination and analysis, and treatment goals. The purpose of this article is to review the definition of CR, its relationship with malocclusion, and the application of this relationship in orthodontic treatment.
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http://dx.doi.org/10.7518/hxkq.2019.05.014 | DOI Listing |
Sci Rep
January 2025
School of Computer Science and Technology, Donghua University, Shanghai, 201620, China.
Extracting high-order abstract patterns from complex high-dimensional data forms the foundation of human cognitive abilities. Abstract visual reasoning involves identifying abstract patterns embedded within composite images, considered a core competency of machine intelligence. Traditional neuro-symbolic methods often infer unknown objects through data fitting, without fully exploring the abstract patterns within composite images and the sequential sensitivity of visual sequences.
View Article and Find Full Text PDFJ Sport Rehabil
January 2025
Department of Hand Surgery, Bridge Hospital, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland.
Context: There is a minimal number of studies of under-21-year-old national football teams, and the literature is injury centric. Particularly, current knowledge is deficient regarding noninjurious medical conditions, such as illnesses and diseases.
Design: The objectives of this study were to analyze the descriptive characteristics of injuries and illnesses or diseases encountered in an under-21 football team during 2 European championship qualification tournaments.
Oral Maxillofac Surg Clin North Am
December 2024
Private Practice, Brooklyn, NY, USA.
Complete arch oral implant treatment using photogrammetry was studied in 77 patients with 111 arches focusing on digitization of clinical records and optimization of the provisional. The aim of the study was to test the hypothesis that patient satisfaction with the provisional prosthesis during the first 4 months of care determined workflow efficiency and success. Digitization of 8 clinical records was done including centric relation, vertical dimension, esthetics, occlusion, inter-arch space, abutment selection, abutment capture, and soft tissue scan.
View Article and Find Full Text PDFExp Hematol
December 2024
Division of Experimental Hematology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Experimental Hematology Group, Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany. Electronic address:
Aging exerts a profound impact on the hematopoietic system, leading to increased susceptibility to infections, autoimmune diseases, chronic inflammation, anemia, thrombotic events, and hematologic malignancies. Within the field of experimental hematology, the functional decline of hematopoietic stem cells (HSCs) is often regarded as a primary driver of age-related hematologic conditions. However, aging is clearly a complex multifaceted process involving not only HSCs but also mature blood cells and their interactions with other tissues.
View Article and Find Full Text PDFPharmaceut Med
December 2024
Medical Affairs Department, AstraZeneca Farmacéutica Spain, C. del Puerto de Somport 21-23, Fuencarral-El Pardo, 28050, Madrid, Spain.
Introduction: The rapidly evolving healthcare landscape has prompted Medical Affairs (MA) departments within pharmaceutical companies to transition from their traditional role as information providers to becoming strategic partners in the healthcare ecosystem. Responding to the increasing complexity of patient needs and stakeholder dynamics within Spain's national health system, this shift emphasizes the importance of aligning MA functions with broader healthcare goals. Effective transformation requires in-depth assessments of stakeholder trends and expectations.
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