Left atrial appendage occlusion: a critical appraisal updated with recent evidence.

Curr Opin Cardiol

Louisville Cardiology Group, Baptist Health Louisville, Louisville Division of Cardiology, Penn State College of Medicine, Pennsylvania, USA.

Published: January 2020

Purpose Of Review: To allow readers to fully appreciate the uncertainties with this novel yet invasive approach to stroke prevention.

Recent Findings: Percutaneous left atrial (LA) appendage occlusion has emerged as potential nonpharmacologic means to prevent stroke and systemic embolism in patients with atrial fibrillation. Yet the evidence underpinning this new technology is not definitive.

Summary: In this review, we consider the internal and external validity of the regulatory trials, pathophysiologic basis for LA appendage occlusion and clinical tradeoffs of the procedure.

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Source
http://dx.doi.org/10.1097/HCO.0000000000000698DOI Listing

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