The supine position is still the most frequently used type of positioning during surgical procedures. Positions other than the supine position lead to physiological alterations that have a relevant influence on the course of anesthesia and surgery. As a matter of principle, hemodynamic stability is at risk because venous blood is pooled in the lower positioned body parts. In addition, head down positions (Trendelenburg position) may lead to an impairment of respiratory function by reducing lung volumes as well as lung compliance. Upright positions (beach chair position) are characterized by a relative hypovolemia accompanied by a reduction of mean arterial pressure, cardiac output and stroke volume, whereas pulmonary functions remain unchanged. Some severe adverse events have been described in the literature (e.g. intraoperative apoplexy, postoperative blindness). The pathophysiological principles and effects of hemodynamic alterations as well as potential strategies to avoid complications are presented and discussed in this lead article. Head down positions, especially the Trendelenburg position, cause a relative (intrathoracic) hypervolemia and an increase in cardiac preload that is usually well-tolerated in patients without heart problems; however, the Trendelenburg position, especially if combined with a capnoperitoneum, significantly impairs pulmonary function, can have a negative effect on intracerebral pressure and may reduce blood flow of intra-abdominal organs. The pathophysiological intraoperative changes caused by Trendelenburg positioning are described and approaches suitable for risk reduction are discussed. The prone position and lateral decubitus position have little influence on the intraoperative homeostasis. Nevertheless, there is an ongoing discussion concerning the efficacy of a 15° left lateral position during caesarean section, which is also discussed in a separate section of this review.
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http://dx.doi.org/10.1007/s00101-019-00674-9 | DOI Listing |
Aerosp Med Hum Perform
January 2025
Introduction: In space, under weightlessness conditions, human brain activity is changed due to the shifting of body fluid and blood toward the cephalic region. This shifting leads to changes in cerebral hemodynamics and, consequently, neurophysiological function, which impacts mental functions like cognition and decision-making capabilities of space travelers. The present study reports the effect of acute exposure to simulated microgravity on cognitive functions and event-related potentials.
View Article and Find Full Text PDFMagnes Res
January 2025
Department of Anaesthesiology & Pain Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Korea, Department of Anaesthesiology & Pain Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.
Although intraoperative magnesium sulphate administration has various advantages, its influence on the occurrence of postoperative acute kidney injury (AKI) remains unclear, particularly in patients undergoing robot-assisted radical prostatectomy (RARP). The steep Trendelenburg position and a high intra-abdominal pressure can render patients susceptible to AKI after surgery. This study aimed to evaluate the effects of intraoperative magnesium sulphate administration on postoperative AKI in patients who underwent RARP.
View Article and Find Full Text PDFSurg Endosc
January 2025
Department of Anesthesiology and Reanimation, Faculty of Medicine, Istınye University Medicalpark Gaziosmanpasa Hospital, Istanbul, Turkey.
Background: The aim of our study is to compare the effect of the 30° reverse Trendelenburg position combined with the beach chair position on respiratory parameters in laparoscopic sleeve gastrectomy (LSG) with the 30° reverse Trendelenburg position alone.
Material And Method: Fifty patients with body mass index > 30 were included in the study. The patients were divided into two groups; in the control group, the standard 30° reverse Trendelenburg.
Perception
January 2025
Hebei Normal University, China.
Exposure to microgravity induces abnormal experiences that may affect the perception of time. Head-down tilts (HDTs) are commonly used to investigate the effects of weightlessness. A -30° HDT is considered an appropriate model to simulate the acute phase of microgravity exposure.
View Article and Find Full Text PDFHealth Sci Rep
January 2025
Faculty of Medicine and Health Science Crewe Campus, University of Buckingham Crewe UK.
Background: Space exploration has become a major interest for scientific and medical research. With increasing duration and frequency of manned space missions, it is crucial to understand the impact of microgravity on the cardiovascular health of astronauts. We focus on this relationship by reviewing literature that explores how microgravity affects several hemodynamic parameters and cardiovascular biomarkers.
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