We demonstrate a logic gate based on interference of forward volume spin waves (FVSWs) propagating in a 54 nm thick, 100 μm wide yttrium iron garnet waveguide grown epitaxially on a garnet substrate. Two FVSWs injected by coplanar waveguides were made to interfere constructively and destructively by varying their phase difference, showing an XNOR logic function. The reflected and resonant waves generated at the edges of the waveguide were suppressed using spin wave absorbers. The observed isolation ratio was 19 dB for a magnetic field of ~2.80 kOe ( = 223 kA m) applied perpendicular to the film. The wavelength and device length were ~8.9 μm and ~53 μm, respectively. Further, the interference state of the SWs was analyzed using three-dimensional radio frequency simulations.
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http://dx.doi.org/10.1038/s41598-019-52889-w | DOI Listing |
Anal Chem
January 2025
Key Laboratory of Laboratory Medicine, Ministry of Education, Zhejiang Provincial Key Laboratory of Medical Genetics, Cixi Biomedical Research Institute, School of Laboratory Medicine and Life sciences, Wenzhou Medical University, Wenzhou 325035, China.
Accurate identification of cancer cells under complex physiological environments holds great promise for noninvasive diagnosis and personalized medicine. Herein, we developed dual-aptamer-based DNA logic-gated series lamp probes (Apt-SLP) by coupling a DNA cell-classifier (DCC) with a self-powered signal-amplifier (SSA), enabling rapid and sensitive identification of cancer cells in a blood sample. DCC is endowed with two extended-aptamer based modules for recognizing the two cascade cell membrane receptors and serves as a DNA logic gate to pinpoint a particular and narrow subpopulation of cells from a larger population of similar cells.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
December 2024
Anhembi Morumbi University (UAM), Rodovia Dr Altino Bondensan 500, São José dos Campos 12247-016, SP, Brazil; Center of Innovation, Technology and Education (CITE), Rodovia Dr Altino Bondensan 500, São José dos Campos 12247-016, SP, Brazil. Electronic address:
The inherent potential for self-assembly is a well-known attribute of organic dye molecules. This work takes advantage of the changes in dye photochemical and photophysical properties produced by the aggregation phenomenon, to investigate the behavior of all-optical modulation in molecular aggregates. The theoretical principles for a dual beam all-optical modulation, as well as the conception of an optical logic gate by exploring the aggregation phenomenon are discussed throughout the article.
View Article and Find Full Text PDFNat Nanotechnol
January 2025
Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech College of Engineering and Emory School of Medicine, Atlanta, GA, USA.
The forward design of biosensors that implement Boolean logic to improve detection precision primarily relies on programming genetic components to control transcriptional responses. However, cell- and gene-free nanomaterials programmed with logical functions may present lower barriers for clinical translation. Here we report the design of activity-based nanosensors that implement AND-gate logic without genetic parts via bi-labile cyclic peptides.
View Article and Find Full Text PDFChem Asian J
December 2024
Guangxi Normal University, School of chemistry and pharmaceutical science, No.15, Yucai Road, 541004, Guilin, CHINA.
The anomalous expression of microRNA poses a serious threat to human life and health safety, and serves as an important biomarker for cancer detection. In this study, a novel magnetic-assisted DNA logic gate nanomachine triggered by miRNA-21 and miRNA-155 was designed based on the trans-cleavage activity of CRISPR/Cas12a activated by a split DNA activator, using only a single crRNA and signal probe, which simplified the detection procedure and complex nucleic acid amplification. The presence of target molecules, miRNA-21 and miRNA-155, can stimulate the DNA walker machine assembled on magnetic beads, which releases activator under the action of DNAzyme.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Physics, Indian Institute of Technology, Patna, 801106, Bihar, India.
A highly effective method for creating a supramolecular metallogel of Ni(II) ions (NiA-TA) has been developed in our work. This approach uses benzene-1,3,5-tricarboxylic acid as a low molecular weight gelator (LMWG) in DMF solvent. Rheological studies assessed the mechanical properties of the Ni(II)-metallogel, revealing its angular frequency response and thixotropic behaviour.
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