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Botulinum toxin type A injection-related suppurative granuloma: a case report. | LitMetric

AI Article Synopsis

  • Botulinum toxin type A (BoNTA) is widely used for esthetic procedures due to its safety, but complications can occur, as shown in a case of painless skin-colored nodules appearing after injection.
  • Histopathological analysis revealed a suppurative granuloma with no detectable organisms, prompting treatment with broad-spectrum antibiotics effective against atypical mycobacteria.
  • After 6 weeks of antibiotic treatment, the nodules improved significantly, and by 6 months, all lesions cleared without scarring.

Article Abstract

Botulinum toxin type A (BoNTA) injection has become increasingly popular for esthetic minimally invasive procedures worldwide, owing to its efficacy and safety. Serious and long-term complications are rare. Here, we report a case of painless skin-colored cutaneous nodules on the face that developed a few days after BoNTA injection. The histopathology revealed a suppurative granuloma which yielded negative results for all organisms on histochemical staining and tissue culture. While waiting for the results of polymerase chain reaction (PCR), we started administration of systemic broad-spectrum antibiotics that were effective against atypical mycobacteria, since suppurative granuloma is usually related to mycobacterial infection, and a negative result of histochemical staining is common among these organisms. The nodules were flattened down after antibiotics started 6 weeks . All lesions were clear without any scar after 6 months of treatment.

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Source
http://dx.doi.org/10.1080/14764172.2019.1690663DOI Listing

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