A 72-year-old man was followed as an outpatient at our hospital for 6 years after surgery for small cell carcinoma of left adrenal gland origin. Follow-up abdominal computed tomography showed a 6-cm mass in the left lower mesentery. The patient underwent open laparotomy. The histological diagnosis was sclerosing mesenteritis. The previous specimens of the left adrenal mass were then re-examined with a microscope, and panniculitis was found around the small cell carcinoma. Both lesions were histologically similar to IgG4-related disease (RD), but they did not completely meet the diagnostic criteria of IgG4-RD clinically or histologically.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056383PMC
http://dx.doi.org/10.2169/internalmedicine.3221-19DOI Listing

Publication Analysis

Top Keywords

sclerosing mesenteritis
8
igg4-related disease
8
small cell
8
cell carcinoma
8
left adrenal
8
mesenteritis mimicking
4
mimicking igg4-related
4
disease 72-year-old
4
72-year-old man
4
man outpatient
4

Similar Publications

Chylous ascites occur when the lymphatic flow is blocked or disrupted, causing a leakage of fluid into the peritoneal space. It can be caused by a number of etiologies and identifying the exact cause can be challenging. We present the case of a 77-year-old man who presented with chylous ascites.

View Article and Find Full Text PDF

Sclerosing Mesenteritis Presenting as Intestinal Occlusion: A Case Report.

Cureus

December 2024

Esophagogastric Surgery, Unidade Local de Saúde (ULS) de Viseu Dão-Lafões, Viseu, PRT.

Article Synopsis
  • Sclerosing mesenteritis is a rare chronic condition that affects the mesenteric fat, involving inflammation and fibrosis without a clear cause, leading to variable symptoms, most commonly abdominal pain.
  • Its diagnosis primarily relies on histological analysis, even though incidental findings have increased due to widespread CT imaging.
  • The prognosis is generally good, but misdiagnosis is common, highlighting the need to consider it in cases of vague abdominal pain to prevent unnecessary treatments, though surgery might be required for severe cases like intestinal blockage.
View Article and Find Full Text PDF
Article Synopsis
  • A 78-year-old male patient presented with persistent vomiting due to a rare case of metastatic urinary bladder cancer, which led to gastric outlet obstruction.
  • Despite recent follow-up showing no disease recurrence, tests revealed duodenal stenosis and abnormal mesenteric fat swelling, initially misinterpreted as inflammation.
  • A laparoscopic exploration confirmed peritoneal carcinomatosis, ultimately identifying urothelial cancer cells, highlighting the need for clinicians to think about metastatic bladder cancer in similar situations.
View Article and Find Full Text PDF

IgG4-related disease for the hematologist.

Hematology Am Soc Hematol Educ Program

December 2024

Division of Hematology, University of British Columbia, Vancouver, British Columbia, Canada; and Division of Hematology, Dalhousie University, Halifax, Nova Scotia, Canada.

Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated disease with many important manifestations in hematopoietic and lymphoid tissue. IgG4 is the least naturally abundant IgG subclass, and the hallmark feature of IgG4-RD is markedly increased IgG4-positive plasma cells (with an IgG4 to IgG ratio >40%) in affected tissue, along with elevated polyclonal serum IgG and IgG4 in most patients. Histological diagnosis is essential, and other key features include storiform fibrosis, lymphoplasmacytic infiltrate, tissue eosinophilia, and obliterative phlebitis.

View Article and Find Full Text PDF

A 57-year-old male with a history of hypertension, diabetes mellitus, and dyslipidemia was found to have elevated carcinoembryonic antigen (CEA) levels during a routine health checkup, leading to an abdominal computed tomography (CT) scan. The scan identified a mesenteric mass with an irregular morphology. Subsequent blood tests indicated no signs of inflammation, and follow-up CEA levels normalized.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!