Sorbonne University, Action Coeur, Inserm UMR_S 1166, Cardiology Institute, Pitié-Salpêtrière Hospital (AP-HP), 75013 Paris, France. Electronic address:
Published: November 2019
AI Article Synopsis
Article Abstract
Background: There is a dearth of updated epidemiological data on the prevalence and annual incidence of coronary artery disease (CAD) and lower extremity artery disease (LEAD) in Western countries.
Aims: To describe the incidence and prevalence of CAD and LEAD, associated medication patterns and long-term outcomes in France.
Methods: This was a retrospective cohort study using French claims data from a representative sample of the French general population. Any hospitalization or long-term disease status for CAD or LEAD between January 2010 and December 2016 was collected to identify incident cases.
Results: Of the 763,338patients screened in the study period, 8559 incident cases of CAD and 4399 of LEAD were identified, with an overall mean follow-up of 2.9±2.0years. The incidence of CAD, LEAD and CAD or LEAD remained stable over the years, and in 2016 were at 33.5 per 10,000person-years, 15.1per 10,000person-years and 42.5 per 10,000person-years, respectively. The prevalence of CAD increased from 3.1% in 2010 to 4.2% in 2016, and LEAD from 1.6% to 2.4%. Most patients received guideline-recommended medication with antithrombotic drugs and lipid-lowering drugs following the index event. However, most of the medications initiated were subsequently discontinued during follow-up. Incident CAD or LEAD was associated with considerable morbidity-particularly an incidence of all-cause hospitalization of 7976.9 per 10,000person-years-and all-cause mortality, with an incidence of 542.8 per 10,000person-years.
Conclusion: In recent years, the prevalence of CAD or LEAD has increased progressively, resulting in considerable morbidity and mortality.
Background: Future clinical management would be improved by accurate and early identification of ACS patients at high CV risk. In non-valvular atrial fibrillation patients, the prognostic risk of thromboembolism has been evaluated using CHA₂DS₂-VASc scores. It has recently been shown to assess the severity of CAD and foresee patient outcomes.
Background: This study aimed to evaluate the effects of different heart rate fluctuation ranges during aerobic training on outcomes in patients with stable coronary artery disease (CAD).
Methods: Ninety-seven patients diagnosed with stable CAD were enrolled between March 2017 and December 2019. Participants were randomly assigned to three groups: the control (CON) group, the medium-intensity heart rate small range (MIS) group, and the medium-intensity heart rate large range (MIL) group.
Department of Electrical Engineering, Convergence IT Engineering, Mechanical Engineering, Medical Device Innovation Center, and Graduate School of Artificial Intelligence, and Medical Device Innovation Center, Pohang University of Science and Technology, Pohang, Republic of Korea; Opticho Inc., Pohang, Republic of Korea. Electronic address:
Objective: Breast cancer is one of the most commonly occurring cancers in women. Thus, early detection and treatment of cancer lead to a better outcome for the patient. Ultrasound (US) imaging plays a crucial role in the early detection of breast cancer, providing a cost-effective, convenient, and safe diagnostic approach.
Background: Periodontitis is a chronic inflammatory disease of the supporting tissue surrounding the teeth. The disease is caused by specific bacteria, such as Porphyromonas gingivalis, which lead to the destruction of periodontal ligaments and alveolar bone.
Objectives: The study aimed to evaluate the relationship between the prevalence of P.
