We discuss the hunt for long-lived particles at the Large Hadron Collider. A motivation is given for such searches, and the experimental challenges are presented. It has become clear in the last few years that the present experiments are not optimally equipped to cover the full phase space of possibilities for such scenarios, so recently small additional experiments have been proposed for specific searches. This article is part of a discussion meeting issue 'Topological avatars of new physics'.
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http://dx.doi.org/10.1098/rsta.2019.0047 | DOI Listing |
PLoS One
January 2025
Curriculum in Toxicology & Environmental Medicine, UNC Chapel Hill, Chapel Hill, North Carolina, United States of America.
Growing evidence supports the importance of extracellular vesicle (EV) as mediators of communication in pathological processes, including those underlying respiratory disease. However, establishing methods for isolating and characterizing EVs remains challenging, particularly for respiratory samples. This study set out to address this challenge by comparing different EV isolation methods and evaluating their impacts on EV yield, markers of purity, and proteomic signatures, utilizing equine/horse bronchoalveolar lavage samples.
View Article and Find Full Text PDFNature
January 2025
Department of Physics, Durham University, Durham, United Kingdom.
Realizing quantum control and entanglement of particles is crucial for advancing both quantum technologies and fundamental science. Substantial developments in this domain have been achieved in a variety of systems. In this context, ultracold polar molecules offer new and unique opportunities because of their more complex internal structure associated with vibration and rotation, coupled with the existence of long-range interactions.
View Article and Find Full Text PDFRep Prog Phys
January 2025
European Organization for Nuclear Research, HCP, CH-1211 GENEVE 23, Geneva, 1211 Geneva 23, SWITZERLAND.
A search for light long-lived particles decaying to displaced jets is presented, using a data sample of proton-proton collisions at a center-of-mass energy of 13.6 TeV, corresponding to an integrated luminosity of 34.7 fb$^{-1}$, collected with the CMS detector at the CERN LHC in 2022.
View Article and Find Full Text PDFProc Jpn Acad Ser B Phys Biol Sci
December 2024
Department of Physics, The University of Tokyo, Tokyo, Japan.
Λ = Λ(1405) plays an essential role in the formation of kaonic nuclear clusters (KNC). The simplest KNC, Kpp, has the structure Λp = (Kp)p, in which a real kaon migrates between two nucleons, mediating super-strong Λp attraction. Production data of Kpp have been accumulated by DISTO, J-PARC E27 and J-PARC E15 experiments.
View Article and Find Full Text PDFAdv Healthc Mater
January 2025
State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Key Laboratory of Biopharmaceutical Preparation and Delivery, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
A key challenge in vaccine development is to induce an effective and durable immune response. Live virus vaccines induce lifelong antibody responses; however, the immune responses induced by inactivated or subunit vaccines decrease gradually. Activation of the germinal center (GC) reaction, which generates long-lived plasma cells (LLPCs), is a key mediator of long-term antibody responses.
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