AI Article Synopsis
- Little is known about how blood clotting affects the drying process of blood pools, especially since clotting usually turns liquid blood into gel.
- A study compared the drying of citrated blood (which has an additive to prevent clotting) to unmodified blood, revealing differences in surface appearance, color, and crack formation during drying.
- Researchers developed a method to reactivate clotting in citrated blood, enabling more accurate studies of the drying process in blood pools.
Article Abstract
Little is currently known about the importance of clotting during the drying of blood pools. While this is of little moment for droplets where drying occurs faster than contact-phase-induced clotting, clotting may significantly influence blood pools drying as it transform a liquid into a gel. To investigate this influence, we compare the drying of citrated and unmodified blood pools at constant haematocrit, showing large morphological differences during drying, both in the surface appearance, in the colour lightness, as well as in the generation and location of cracks. Further, we designed a clotting-reactivation protocol which allowed recovering the morphological evolution of pure blood drying while using citrate-sampled blood. This result opens the way to the use of citrated blood in blood pools investigations.
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| http://dx.doi.org/10.1016/j.forsciint.2019.110008 | DOI Listing |
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