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Hippocampal neuronal activity is aligned with action plans.
Nature
January 2025
Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, USA.
Neurons in the hippocampus are correlated with different variables, including space, time, sensory cues, rewards and actions, in which the extent of tuning depends on ongoing task demands. However, it remains uncertain whether such diverse tuning corresponds to distinct functions within the hippocampal network or whether a more generic computation can account for these observations. Here, to disentangle the contribution of externally driven cues versus internal computation, we developed a task in mice in which space, auditory tones, rewards and context were juxtaposed with changing relevance.
View Article and Find Full Text PDFMunchausen Syndrome Presented as Guillain-Barré Syndrome: A Case Report and Literature Review.
Cureus
January 2025
Department of Neurology, Unidade Local de Saúde da Arrábida, Setúbal, PRT.
Munchausen syndrome (MS), a complex form of factitious disorder (FD), presents significant diagnostic and management challenges in emergency and hospital settings. Patients deliberately fabricate or induce symptoms to gain medical attention, often leading to unnecessary interventions, resource misallocation, and iatrogenic harm. This study highlights the diagnostic complexity and the need for multidisciplinary management of Munchausen syndrome through a detailed case report and literature review.
View Article and Find Full Text PDF"No One Really Prepares You": Lived Experiences of Women Division Chiefs in Academic Medicine.
J Womens Health (Larchmt)
December 2024
Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut, USA.
Although women have comprised at least 50% of medical school classes for decades, women remain underrepresented in leadership positions. Although the proportion of women division chiefs in the U.S.
View Article and Find Full Text PDFElectrostatic Orientation of Optically Asymmetric Janus Particles.
ACS Omega
December 2024
Metamaterials Laboratory, Electrical and Computer Engineering Department, Northeastern University, Boston, Massachusetts 02115, United States.
Janus micro- and nanoparticles, featuring unique dual-interface designs, are at the forefront of rapidly advancing fields such as optics, medicine, and chemistry. Accessible control over the position and orientation of Janus particles within a cluster is crucial for unlocking versatile applications, including targeted drug delivery, self-assembly, micro- and nanomotors, and asymmetric imaging. Nevertheless, precise mechanical manipulation of Janus particles remains a significant practical challenge across these fields.
View Article and Find Full Text PDFStabilized Oxygen Vacancy Chemistry toward High-Performance Layered Oxide Cathodes for Sodium-Ion Batteries.
ACS Nano
December 2024
Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Negative Carbon Technologies, Soochow University, Suzhou 215123, China.
Anionic redox has emerged as a transformative paradigm for high-energy layered transition-metal (TM) oxide cathodes, but it is usually accompanied by the formation of anionic redox-mediated oxygen vacancies (OVs) due to irreversible oxygen release. Additionally, external factor-induced OVs (defined as intrinsic OVs) also play a pivotal role in the physicochemical properties of layered TM oxides. However, an in-depth understanding of the interplay between intrinsic and anionic redox-mediated OVs and the corresponding regulation mechanism of the dynamic evolution of OVs is still missing.
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