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Rivaroxaban plus aspirin for cardiovascular protection: Rationale for the vascular dose and dual pathway inhibition. | LitMetric

AI Article Synopsis

  • The review highlights the use of dual pathway inhibition to improve treatment outcomes for patients with coronary or peripheral artery disease.
  • It combines low-dose rivaroxaban (2.5 mg twice daily) to decrease thrombin generation and aspirin (100 mg once daily) to lower platelet activation.
  • This combination therapy has been approved for secondary prevention in patients already diagnosed with these vascular conditions.

Article Abstract

This review provides the rationale for dual pathway inhibition with the combination of low-dose rivaroxaban (2.5 mg twice daily) to attenuate thrombin generation and aspirin (100 mg once daily) to reduce platelet activation. Such therapy has been licensed for secondary prevention in patients with coronary or peripheral artery disease.

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Source
http://dx.doi.org/10.1016/j.thromres.2019.09.033DOI Listing

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