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Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) syndrome is a rare central nervous system inflammatory disorder with an unknown pathophysiology. We present the case of a 51-year-old female exhibiting clinical and radiological features consistent with CLIPPERS syndrome. She manifested diplopia, vertigo, gait ataxia, and lower limb asthenia, accompanied by impaired tandem gait, right sixth nerve palsy, and coarse horizontal nystagmus during the physical examination.
View Article and Find Full Text PDFKLHL11-associated rhomboencephalitis presenting as clippers-like syndrome.
Neurol Sci
November 2024
Department of Laboratory Medicine, West China Hospital of Sichuan University, No.37 Guoxue Road, Chengdu, 610041, Sichuan, China.
Case report: Hand-arm vibration syndrome in a dental technician.
Front Public Health
October 2024
Department of Occupational and Environmental Medicine, Singapore General Hospital, Singapore, Singapore.
Article Synopsis
- Occupational exposure to vibration from hand-held tools can lead to hand-arm vibration syndrome (HAVS), as shown in the case of a 39-year-old dental technician who experienced chronic wrist pain, numbness, and tingling for three years after five years of repetitive tool use.
- She was diagnosed with bilateral median nerve neuropathy, mild carpal tunnel syndrome, and had MRI results indicating soft tissue damage due to repetitive strain injury, particularly in her dominant right wrist.
- A workplace health risk assessment identified high-risk tasks associated with her symptoms, leading to modifications and monitoring protocols that helped stabilize her condition.
Article Synopsis
- Paraproteinemias are a diverse group of disorders in plasma cells that produce abnormal proteins, leading to various symptoms, including peripheral neuropathies.
- A case study of a 71-year-old woman showed her initial symptoms of paresthesias and ataxic gait were misdiagnosed as CLIPPERS syndrome, but later revealed a monoclonal IgM presence.
- After treatment for the underlying condition improved her mobility, she faced new challenges with osteoporosis and fractures due to prolonged corticosteroid treatment, illustrating the complexity of her condition.
[The central vein sign in the differential diagnosis of multiple sclerosis].
Zh Nevrol Psikhiatr Im S S Korsakova
August 2024
Federal Center for Brain Research and Neurotechnology, Moscow, Russia.
Article Synopsis
- The study aimed to assess the central vein sign (CVS) as a potential diagnostic marker for multiple sclerosis (MS) and other related brain conditions through clinical evaluations and MRI data.
- Results indicated that while CVS is sensitive for diagnosing MS, it lacks specificity, making it unreliable as a standalone diagnostic tool.
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