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| http://dx.doi.org/10.2215/CJN.10370819 | DOI Listing |
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Transforming Medicine: Cutting-Edge Applications of Nanoscale Materials in Drug Delivery.
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January 2025
CAS, a division of the American Chemical Society, Columbus, Ohio 43210, United States.
Since their inception in the early 1960s, the development and use of nanoscale materials have progressed tremendously, and their roles in diverse fields ranging from human health to energy and electronics are undeniable. The application of nanotechnology inventions has revolutionized many aspects of everyday life including various medical applications and specifically drug delivery systems, maximizing the therapeutic efficacy of the contained drugs by means of bioavailability enhancement or minimization of adverse effects. In this review, we utilize the CAS Content Collection, a vast repository of scientific information extracted from journal and patent publications, to analyze trends in nanoscience research relevant to drug delivery in an effort to provide a comprehensive and detailed picture of the use of nanotechnology in this field.
View Article and Find Full Text PDFDrivers of Palliative Care and Hospice Use Among Patients With Advanced Lung Cancer.
Cancer Med
January 2025
Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Purpose: Despite rigorous evidence of improved quality of life and longer survival, disparities in the utilization of palliative and hospice care persist for racial and ethnic minority patients with cancer. This study evaluated the impact of psychosocial factors on utilization of these services.
Methods: Patients with advanced lung cancer were recruited at a large academic urban hospital.
The Complete Inpatient Record Using Comprehensive Electronic Data (CIRCE) project: A team-based approach to clinically validated, research-ready electronic health record data.
Learn Health Syst
January 2025
Department of Biostatistics, Epidemiology and Informatics University of Pennsylvania Perelman School of Medicine Philadelphia Pennsylvania USA.
Introduction: The rapid adoption of electronic health record (EHR) systems has resulted in extensive archives of data relevant to clinical research, hospital operations, and the development of learning health systems. However, EHR data are not frequently available, cleaned, standardized, validated, and ready for use by stakeholders. We describe an in-progress effort to overcome these challenges with cooperative, systematic data extraction and validation.
View Article and Find Full Text PDFA highly accurate family of stable and convergent numerical solvers based on Daftardar-Gejji and Jafari decomposition technique for systems of nonlinear equations.
MethodsX
December 2024
Institute of Computer Science, University of Silesia, Bedzinska 39, Sosnowiec, 41-200, Poland.
This study introduces a family of root-solvers for systems of nonlinear equations, leveraging the Daftardar-Gejji and Jafari Decomposition Technique coupled with the midpoint quadrature rule. Despite the existing application of these root solvers to single-variable equations, their extension to systems of nonlinear equations marks a pioneering advancement. Through meticulous derivation, this work not only expands the utility of these root solvers but also presents a comprehensive analysis of their stability and semilocal convergence; two areas of study missing in the existing literature.
View Article and Find Full Text PDFThe clinical course and outcomes following arthroscopic frozen shoulder 360° release.
JSES Int
November 2024
Queensland Unit for Advanced Shoulder Research (QUASR), Queensland University of Technology, Brisbane, Australia.
Background: Frozen shoulder (FS) is a debilitating inflammatory condition affecting the shoulder capsule that causes significant pain and stiffness. Its etiology, pathophysiology, and treatment remain poorly understood. Although regarded as self-limiting, FS can have profound implications on the activities of daily living and usually takes 1-4 years to resolve on its own accord.
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