Objectives: Marathoners rely on expert-opinion and the anecdotal advice of their peers when devising their training plans for an upcoming race. The accumulation of results from multiple scientific studies has the potential to clarify the precise training requirements for the marathon. The purpose of the present study was to perform a systematic review, meta-analysis and meta-regression of available literature to determine if a dose-response relationship exists between a series of training behaviours and marathon performance.
Design: Systematic review, meta-analysis and meta-regression.
Methods: A systematic search of multiple literature sources was undertaken to identify observational and interventional studies of elite and recreational marathon (42.2km) runners.
Results: Eighty-five studies which included 137 cohorts of runners (25% female) were included in the meta-regression, with average weekly running distance, number of weekly runs, maximum running distance completed in a single week, number of runs ≥32km completed in the pre-marathon training block, average running pace during training, distance of the longest run and hours of running per week used as covariates. Separately conducted univariate random effects meta-regression models identified a negative statistical association between each of the above listed training behaviours and marathon performance (R 0.38-0.81, p<0.001), whereby increases in a given training parameter coincided with faster marathon finish times. Meta-analysis revealed the rate of non-finishers in the marathon was 7.27% (95% CI 6.09%-8.65%).
Conclusions: These data can be used by athletes and coaches to inform the development of marathon training regimes that are specific to a given target finish time.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.jsams.2019.09.013 | DOI Listing |
PLoS One
January 2025
Institute of Primary Care, University of Zurich, Zurich, Switzerland.
Background: Several single race events (5 km, 10 km, half-marathon, marathon, ultra-marathon) in different countries and different years have been analyzed in multiple studies, representing the rising interest in endurance-based activity and thus physical health. With focus on participation numbers, performance or sex difference, many single study results were obtained. The running trends in a whole country covering a longer period of time and several race distances are missing so far.
View Article and Find Full Text PDFJ Prev Alzheimers Dis
January 2025
Alzheimer's Drug Discovery Foundation, New York, NY, USA. Electronic address:
There is growing consensus in the Alzheimer's community that combination therapy will be needed to maximize therapeutic benefits through the course of the disease. However, combination therapy raises complex questions and decisions for study sponsors, from preclinical research through clinical trial design to regulatory, statistical, and operational considerations. In January 2024, the Alzheimer's Drug Discovery Foundation convened an expert advisory board to discuss the key considerations in each of these areas.
View Article and Find Full Text PDFJ Cardiothorac Surg
January 2025
Section of Cardiothoracic Surgery, Department of Heart Disease, Haukeland University Hospital, Jonas Lies vei 65, 5021, Bergen, Norway.
Background: A broncho-esophageal fistula (BEF) is a medical and surgical disaster. Treatment of BEF is often limited to palliative stent treatment that may migrate or cause erosions and tissue necrosis. Surgical repair of BEF is the only established definite treatment.
View Article and Find Full Text PDFCells
December 2024
Workgroup Endocrinology of Farm Animals, Research Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.
Metabolic flexibility describes the capability to switch between oxidative fuels depending on their availability during diet or exercise. In a previous study, we demonstrated that in response to training, marathon (DUhTP) mice, paternally selected for high treadmill performance, are metabolically more flexible than unselected control (DUC) mice. Since exercise-associated metabolic flexibility can be assessed by indirect calorimetry or partially by circulating lactate concentrations, we investigated these parameters in DUhTP and DUC mice.
View Article and Find Full Text PDFBMC Cardiovasc Disord
January 2025
Department of Ultrasonography, Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Background: Long-term endurance training is associated with structural, functional, and biochemical markers of cardiac dysfunction in highly trained athletes. Many studies have focused on structural changes in the right ventricle (RV) and few have examined functional adaptation of the right ventricle. This meta-analysis aims to compare the changes in right ventricular systolic function between endurance athletes and controls before and after exercise using speckle tracking echocardiography (STE).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!