Approach to Cushing's syndrome in pregnancy: two cases of Cushing's syndrome in pregnancy and a review of the literature.

Ann Transl Med

Department of Endocrinology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350001, China.

Published: September 2019

AI Article Synopsis

  • Cushing's syndrome (CS) is a rare condition that can occur during pregnancy, and this article aims to provide a therapeutic approach for managing it.
  • The article discusses two case studies of CS in pregnant women and emphasizes the importance of early diagnosis and a clinical approach for those without prior CS diagnosis.
  • It outlines therapeutic strategies such as glucocorticoid replacement during critical periods and includes assessments of both the physiological and psychological well-being of the patients.

Article Abstract

Cushing's syndrome (CS) rarely occurs during pregnancy. The primary aim of this article is to propose a therapeutic approach to CS in pregnancy. Here, we present two cases of CS in pregnancy and a literature review. This article proposes the early diagnostic points, especially the clinical approach to this medical condition, mainly for pregnant women without a previous diagnosis of CS. More importantly, we present therapeutic strategies for CS during pregnancy, especially glucocorticoid replacement for perioperative, postoperative, and perinatal periods in pregnant women with CS in order to minimize complications for both mother and fetus. At the same time, we also assess the anxiety status of patients. This article summarizes the approach to CS in pregnancy, not only with a physiological assessment but with a psychological assessment as well.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803221PMC
http://dx.doi.org/10.21037/atm.2019.07.94DOI Listing

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