Childhood asthma is insufficiently controlled in a large number of patients, highlighting the need for improved provision of paediatric asthma care. This paper presents consensus criteria for a paediatric asthma clinic. These are intended to provide a basis for the delivery of asthma care to children in primary and secondary care clinics.
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http://dx.doi.org/10.1038/pcrj.2003.16 | DOI Listing |
Allergy Asthma Clin Immunol
December 2024
Division of Allergy, Department of Pediatrics, Dalhousie University, IWK Health Centre, Halifax, NS, Canada.
Food allergy is defined as an adverse immunologic response to a food. Immunoglobulin E (IgE)-mediated reactions to foods are associated with a broad range of signs and symptoms that may involve any of the following body systems: the skin, gastrointestinal tract, respiratory tract, and cardiovascular system. IgE-mediated food allergy is a leading cause of anaphylaxis.
View Article and Find Full Text PDFJ Allergy Clin Immunol Pract
December 2024
Division of Gastroenterology, Phoenix Children's Hospital, Phoenix, AZ, United States; Division of Allergy and Immunology, Phoenix Children's Hospital, Phoenix, AZ, United States. Electronic address:
J Allergy Clin Immunol Pract
December 2024
Division of Biostatistics and Epidemiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, College of Medicine, Cincinnati, OH; Division of Asthma Research, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, College of Medicine, Cincinnati, OH.
Background: Total serum immunoglobulin E (TsIgE) has not been examined in children with food allergy.
Objective: Evaluate associations of TsIgE with patient, household, environmental and community-level characteristics among children with food allergy.
Method: Linear mixed effect models of data from 398 Black and/or African American (B/AA) and White and/or European American (W/EA) children with allergist-diagnosed food allergy from the multi-center, observational cohort FORWARD; TsIgE in kU/L was the primary outcome measure.
World Allergy Organ J
December 2024
Department of Pediatrics, Pediatric Allergy and Pulmonology Unit, University of Chieti-Pescara, Chieti, Italy.
Basophilic granulocytes, containing and releasing histamine after a specific allergy stimulation, are directly involved in IgE-mediated allergic reactions. CD63 is a transmembrane protein of secretory lysosomes of basophils and its upregulation is related with the release of histamine to the extracellular space during IgE-mediated allergic reactions. Basophil activation test (BAT) measures the activation of circulating basophils upon the stimulation of living blood cells with specific allergens.
View Article and Find Full Text PDFTurk J Med Sci
December 2024
Division of Pediatric Pulmonology, Department of Pediatrics, Faculty of Medicine, İstinye University, İstanbul, Turkiye.
Background/aim: Innate-like T lymphocytes are a recently defined group of T cells comprising mainly mucosa-associated invariant T (MAIT) cells. The relationship between MAIT cells and childhood asthma is controversial. In this study, we aimed to determine the role of MAIT cells in patients with allergic asthma (AA) and nonallergic asthma (NAA).
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