Pyrroloquinolone A, a new alkaloid and other phytochemicals from L. with antioxidant and anticholinesterase activities.

A new alkaloid pyrroloquinolone A (), along with fifteen known compounds were isolated from the petroleum ether, EtOAc and -BuOH extracts of the whole plant L. Their structures were elucidated on the basis of extensive spectroscopic analysis including 1D- and 2D-NMR and HR-ESI-MS techniques. This is the first report of alkaloids in the genus . Some of the isolated compounds and extracts were evaluated for their antioxidant potential (scavenging activity of DPPH and ABTS radicals, and reducing Fe and Cu power assays) and acetylcholinesterase and butyrylcholinesterase inhibitory activities. Compounds and showed good antioxidant capacity compared to ascorbic acid, BHA, and BHT used as standards, whereas compounds and exhibited good anticholinesterase activities compared to galantamine used as standard.