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Corpus cavernosum and tunica albuginea reconstruction by tissue engineering: towards functional erectile structures regeneration.
BMC Urol
December 2024
Department of Cardiovascular Surgery, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, China.
Background: Current treatments for penile erectile structures reconstruction are limited and remain a great challenge in clinical practice. Tissue engineering techniques using different seed cells and scaffolds to construct a neo-tissue open promising avenues for penile erectile structures repair and replacement and show great promise in the restoration of: structure, mechanical property, and function which matches the original tissue.
Methods: A comprehensive literature review was conducted by accessing the NCBI PubMed, Cochrane, and Google Scholar databases from January 1, 1990, to January, 1, 2022 using the search terms "Tissue engineering, Corpus cavernosum (CC), Tunica albuginea (TA), Acellular Matrix, Penile Reconstruction".
Multicenter Evaluation of Morbidity and Predictors of Response to Imiquimod Treatment for Penile Intraepithelial Neoplasia.
Eur Urol Open Sci
January 2025
Department of Urology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Introduction And Objective: Imiquimod (IQ) is an immunomodulator used in the management of penile intraepithelial neoplasia (PeIN) lesions. However, IQ treatment may be associated with bothersome side effects (SEs). To date, studies reporting on this morbidity and evaluating predictors of response to IQ are scarce and included small cohorts.
View Article and Find Full Text PDFAltieri modified Nesbit corporoplasty for the treatment of penile curvature: Comparison of local anesthesia vs loco-regional anesthesia on the clinical outcomes.
Arch Ital Urol Androl
October 2024
Department of Medicine and Health Sciences "V. Tiberio", University of Molise, Campobasso.
Objective: To compare the safety profile and clinical outcomes of Altieri-modified Nesbit corporoplasty using two different anesthesia methods including spinal anesthesia and local anesthesia.
Materials And Methods: A total of 40 patients with congenital penile curvature (CPC) and Peyronie's disease (PD) underwent Altieri-modified Nesbit corporoplasty. Group 1 (n = 20) received spinal anesthesia, and Group 2 (n = 20) received local anesthesia.
Prospective validation of clino-radio-pathological risk scoring system (CRiSS) for prediction of inguinal lymph-nodes metastasis in squamous cell carcinoma of penis.
Urol Oncol
December 2024
Department of Surgical Oncology, The Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India.
Objective: To prospectively validate the diagnostic performance of Clino-radio-pathological Risk Scoring System (CRiSS) for prediction of inguinal lymph-node metastasis (ILNM) in squamous cell carcinoma of penis.
Materials And Methods: A prospective observational study of all patients with SCC penis was conducted between January 1, 2021, and December 31, 2023, at our institute. Data regarding all CRiSS parameters and MRI features of >8mm size and presence of necrosis or irregular outline were recorded, and patients were assigned CRiSS scores and groups.
Utilization of subcutaneous indwelling 2-0 silk thread for inner plate frenulum alignment in circumcision using a disposable circumcision suture device: A modified surgical technique.
Surgery
December 2024
Department of Urology and Andrology, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi, Hubei, China. Electronic address:
Background: This prospective nonrandomized controlled study aimed to compare the surgical outcomes, postoperative complications, and patient experiences between a modified circumcision technique using a disposable circumcision suture device and the standard circumcision method using a disposable circumcision suture device in Chinese patients with excess foreskin or phimosis at our department of urology and andrology.
Materials And Methods: A total of 456 patients underwent circumcision at our center from May 2021 to September 2022, with 228 patients in the modified disposable circumcision suture device group (mean age: 29.8 years; range: 16.
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