AI Article Synopsis
- The study explores the characteristics and treatment patterns of nonmetastatic castration-resistant prostate cancer (nmCRPC) patients across the US, Europe, and Japan, based on data from the 2015-2017 Ipsos Global Oncology Monitor Database.
- A total of 2,065 patients were analyzed, with a median age of 74-80 years, a significant portion diagnosed at stage III, and most being treated by urologists.
- Initial treatments mainly included hormone therapies, but over time, there was a shift towards chemotherapy and newer treatment options as patients progressed in their nmCRPC treatment journey.
Article Abstract
We conducted this study to describe nonmetastatic castration-resistant prostate cancer (nmCRPC) patient characteristics and treatment patterns in the US, Europe and Japan. Descriptive analyses were conducted using the 2015-2017 Ipsos Global Oncology Monitor Database. A total of 2065 (442 in the US, 509 in Europe and 1114 in Japan) patients (median age: 74-80 years; stage III at diagnosis 38.5%; Eastern Cooperative Oncology Group [ECOG] score ≤1: 79.4%; treated by urologist 88.4%) were included in the analytic cohort. Luteinizing hormone-releasing hormone agonists and antiandrogens were the most commonly used first regimen treatments. With subsequent nmCRPC regimens their use decreased, while the use of chemotherapy, corticosteroids, androgen synthesis inhibitors and second-generation androgen receptor inhibitors increased. These data represent real-world treatment patterns in nmCRPC.
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| http://dx.doi.org/10.2217/fon-2019-0563 | DOI Listing |
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