Melanosis of the bladder, also known as melanosis vesicae, refers to presence of pigment in bladder mucosa. A rare phenomenon, however, it can be confused with the primary or metastatic melanoma of the bladder. Therefore, knowledge of the entity can prevent over diagnosis of this benign entity. We are reporting a case of melanosis of bladder in a 69 year old male with prolonged history of LUTS and bladder diverticulae. Cystoscopic examination showed black patches and biopsy revealed pigmentation in the epithelium and underlying lamina propria. Special stains identified the pigment to be melanin. No malignant cells were identified.
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http://dx.doi.org/10.1016/j.eucr.2019.100916 | DOI Listing |
Cureus
December 2024
Urology, Rotherham District General Hospital, Rotherham, GBR.
Bladder melanosis is a rare and poorly understood condition involving melanin pigmentation within the urothelial mucosa. Cases often present with haematuria, urinary obstructive symptoms, or cystitis. While generally considered benign, its potential association with malignancy warrants regular monitoring, as cases have previously been reported of an association with urothelial carcinoma and melanoma, although it is unclear whether there is a causal relationship.
View Article and Find Full Text PDFInt J Surg Case Rep
January 2025
Urology A Department, University Hospital IBN SINA, Morocco.
Introduction And Importance: Melanosis of the bladder is a rare condition defined by the development of melanin in the bladder's urothelium and/or macrophages in the lamina propria. This condition first became known in humans in 1986, with fewer than 30 cases described in the English medical literature to date.
Case Report: We present the rare case of bladder melanosis affecting an 85-year-old patient.
J Surg Case Rep
May 2024
Department of Pathology and Laboratory Medicine, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, United States.
Urol Case Rep
March 2024
Detroit Medical Center Urology Residency, Harper Professional Building 4160 John R St. Suite 1017, Detroit, MI, 48201, USA.
Background: Melanosis vesicae is a rare condition characterized by the deposition of melanin within the bladder urothelium.
Case Presentation: We present a case of a 72-year-old male with a history of recurrent urinary retention, bladder diverticula, and concurrent Aerococcus urinary tract infection who presented with left-sided abdominal pain. Cystoscopy revealed diffuse black splotch lesions throughout the bladder and two diverticula.
Urologie
November 2023
Klinik für Urologie, Kantonsspital St. Gallen, Rorschacher Str. 95, 9007, St. Gallen, Schweiz.
Melanosis of the urinary bladder is an extremely rare benign condition in which melanin deposits occur in the urothelial and stromal cells. We report such a case in which melanosis of the urinary bladder was detected in a 55-year-old woman with known multiple sclerosis during an extended workup due to urinary urgency complaints. The findings were confirmed by biopsy.
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