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Transdermal Buprenorphine Patch in the Management of Postoperative Acute Pain Following Mandibular Resection and Reconstruction.
J Oral Maxillofac Surg
December 2024
Associate Professor, Department of Dentistry, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Background: Transdermal buprenorphine is used for the management of postoperative pain. Its effectiveness for the postoperative pain management following mandibular resection and reconstruction has yet to be evaluated.
Purpose: To evaluate the efficacy of transdermal buprenorphine patch (TBP) in managing postoperative pain after mandibular resection and reconstruction with anterior iliac crest graft.
Another lesson from the earthquake: Transdermal fentanyl dependence in two child victims.
Turk J Phys Med Rehabil
September 2024
Department of Physical Medicine and Rehabilitation, Ankara University Faculty of Medicine, Ankara, Türkiye.
Thousands died in the Kahramanmaraş-centered earthquake in February 2023, and even more were injured. Some were administered transdermal fentanyl patches (TFPs) due to severe pain. Two pediatric patients, both severely injured victims of the earthquake, developed dependence on TFPs and experienced difficulties during the cessation of fentanyl treatment.
View Article and Find Full Text PDFTransdermal Ketoprofen Versus Fentanyl Patches for Pain Management Post-cesarean Section: A Comparative, Randomized, Double-Blind Study.
Cureus
November 2024
Department of Anaesthesiology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.
Introduction: Postoperative pain management after a cesarean section is essential to promote mother-infant bonding and ease of breastfeeding. Transdermal patches present a viable alternative to oral medications, offering controlled drug delivery and better bioavailability while avoiding first-pass metabolism, all of which can facilitate smoother recovery and rehabilitation.
Methods: This comparative, randomized, double-blind study was conducted on 70 parturients scheduled for cesarean section under spinal anesthesia, classified as ASA II.
A neural circuit from paratenial thalamic nucleus to anterior cingulate cortex for the regulation of opioid-induced hyperalgesia in male rats.
Neurobiol Dis
December 2024
Department of Anesthesiology, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan, 430030, Hubei, China. Electronic address:
Prolonged use of opioids can lead to increased sensitivity to painful stimuli, a condition referred to as opioid-induced hyperalgesia (OIH). However, the mechanisms underlying this contradictory situation remain unclear. This study elucidates the pivotal role of the paratenial thalamic nucleus (PT)-anterior cingulate cortex (ACC) neuronal circuit in the development of OIH in male rats.
View Article and Find Full Text PDFBilateral Globus Pallidus Lesions and Delayed Hypoxic Encephalopathy Induced by Overuse of Transdermal Fentanyl Patches.
Cureus
October 2024
Health Science, Fukui Health Science University, Fukui, JPN.
We describe a rare case of bilateral globus pallidus lesions (BPL) and delayed hypoxic encephalopathy (DHE) induced by the overuse of transdermal fentanyl patches. The patient was a 54-year-old woman, who had a history of unexplained, intractable anal pain, for which several medications were prescribed, but with very limited effectiveness. Four days prior to admission, she was newly prescribed transdermal fentanyl patches at a dose of 4 mg/day.
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