Phytochemical investigation on the rhizomes of C.Chr. led to the isolation of three new compounds, named matteuinterins A-C (), together with seven known compounds (). Their structures were elucidated by extensive NMR analyses and chemical derivatization. Compounds - were evaluated for their anti-inflammatory activities on PGE release in LPS-stimulated RAW 264.7 murine macrophages. Compounds and exhibited inhibitory effect on PGE production in LPS-activated murine macrophages with IC values of 17.8 ± 1.5 and 30.3 ± 2.1 μM, respectively.[Formula: see text].
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/10286020.2019.1681410 | DOI Listing |
Publication Analysis
Top Keywords
matteuinterins a-c
8
murine macrophages
8
a-c three
4
three glycosides
4
glycosides rhizomes
4
rhizomes phytochemical
4
phytochemical investigation
4
investigation rhizomes
4
rhizomes cchr
4
cchr led
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!