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Integrated analysis of the prevalence and influencing factors of poststroke dysphagia.
Eur J Med Res
January 2025
Clinical Research and Big Data Center, South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, China.
Objectives: Poststroke dysphagia (PSD) is a common complication after stroke but there is limited information on its global prevalence and influencing factors, such as spatial, temporal, demographic characteristics, and stroke-related factors. Our study seeks to fill this knowledge gap by exploring the overall prevalence of PSD and its influencing factors.
Methods: A search of English-language literature from database inception from 2005 until May 2022 was performed using PubMed, Embase, Web of Science, Cochrane Library, and Scopus.
Polycystic Ovary Syndrome and the Potential for Nanomaterial-Based Drug Delivery in Therapy of This Disease.
Pharmaceutics
December 2024
School of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming 650500, China.
Polycystic ovary syndrome (PCOS) is the predominant endocrine disorder among women of reproductive age and represents the leading cause of anovulatory infertility, which imposes a considerable health and economic burden. Currently, medications used to treat PCOS can lead to certain adverse reactions, such as affecting fertility and increasing the risk of venous thrombosis. Drug delivery systems utilizing nanomaterials, characterized by prolonged half-life, precision-targeted delivery, enhanced bioavailability, and reduced toxicity, are currently being employed in the management of PCOS.
View Article and Find Full Text PDFMitochondrial Alterations in Alzheimer's Disease: Insight from the 5xFAD Mouse Model.
Mol Neurobiol
December 2024
Institute of Health Science, Department of Biophysics, Acibadem Mehmet Ali Aydinlar University, Kayisdagi Cad. No. 32, Atasehir, Istanbul, Turkey.
Mitochondrial dysfunction is increasingly recognized as a key factor in Alzheimer's disease (AD) pathogenesis, but the precise relationship between mitochondrial dynamics and proteinopathies in AD remains unclear. This study investigates the role of mitochondrial dynamics and function in the hippocampal tissue and peripheral blood mononuclear cells (PBMCs) of 5xFAD transgenic mice, as a model of AD. The levels of mitochondrial fusion proteins OPA1 and MFN2 and fission proteins DRP1 and phospho-DRP1 (S616) at 3, 6, and 9 months of age were assessed.
View Article and Find Full Text PDFPublicly available Australian hospital data on infant feeding: A review and comparative analysis of outcomes.
Women Birth
September 2024
School of Nursing and Midwifery, Western Sydney University, Australia.
Background: Breastfeeding is the optimal method of providing infant nutrition. The Baby Friendly Health Initiative (BFHI) is a global strategy to promote breastfeeding. This study aimed to explore infant feeding data in Australian hospitals and compare outcomes between BFHI and non-BFHI accredited hospitals, and between public and private hospitals.
View Article and Find Full Text PDFCisternostomy is not beneficial to reduce the occurrence of post-traumatic hydrocephalus in Traumatic Brain Injury.
Acta Neurochir (Wien)
April 2024
Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Background: The Cisternostomy is a novel surgical concept in the treatment of Traumatic Brain Injury (TBI), which can effectively drain the bloody cerebrospinal fluid from the skull base cistern, reduce the intracranial pressure, and improve the return of bone flap, but its preventive role in post-traumatic hydrocephalus (PTH) is unknow. The purpose of this paper is to investigate whether Cisternostomy prevents the occurrence of PTH in patients with moderate and severe TBI.
Methods: A retrospective analysis of clinical data of 86 patients with moderate and severe TBI from May 2019 to October 2021 was carried out in the Brain Trauma Center of Tianjin Huanhu Hospital.
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