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Unusual Management of a Rare Case of Methimazole-Resistant Graves Disease.
JCEM Case Rep
January 2025
Baylor University Medical Center, Dallas, TX 75246, USA.
Article Synopsis
- Graves disease (GD) is the main cause of hyperthyroidism but often shows different symptoms like tachycardia and weight loss instead of the typical signs.
- Treatment options include antithyroid drugs (ATDs), radioactive iodine (RAI), and surgery, each with notable side effects and potential complications such as ATD resistance.
- A complex case study of a 58-year-old woman with MMI-resistant GD illustrates the difficulties in treatment, leading to successful management with RAI therapy after unsuccessful attempts with high doses of MMI.
Pretibial hematoma as a cause of significant health issue in an elderly traveler.
Int Marit Health
October 2024
Department of Tropical Medicine and Epidemiology, Institute of Maritime and Tropical Medicine, Faculty of Health Sciences, Medical University of Gdańsk, Poland.
This paper presents a case of a 77-year-old patient diagnosed with type 2 cardio-renal syndrome, who has undergone a Transcatheter Aortic Valve Implantation surgery due to aortic stenosis associated with permanent atrial fibrillation and type 2 diabetes. This patient, despite their multi-morbidity, undertook family travels to Egypt. Despite disease symptoms and plethora of medication, the patient did not seek medical advice on preventative measures or potential health risks prior to the departure.
View Article and Find Full Text PDFRapid Efficacy of riSankizumab in pretibial psoriasis invOLVEment: RESOLVE.
Drugs Context
September 2024
Department of Medical-Surgical Sciences and Biotechnologies, Dermatology Unit "Daniele Innocenzi", Sapienza University of Rome, Polo Pontino, Italy.
Background: Despite extraordinary improvements in the management of psoriasis in recent times, some areas of the body, such as the pretibial area, still show an unsatisfactory response and a more significant impact on patient quality of life. This multicentre study focuses on psoriasis affecting sensitive areas (particularly the pretibial area), its impact on quality of life and the therapeutic response to risankizumab.
Methods: This multicentre prospective observational study recruited patients with moderate-to-severe psoriasis with pretibial area involvement.
Graves' disease thyroid dermopathy: a case report.
J Med Case Rep
April 2024
Department of Pediatrics, King Faisal Specialist Hospital and Research Centre, Al Takhassousi & 12713, 11211, Riyadh, Saudi Arabia.
Article Synopsis
- Graves' disease is an autoimmune disorder leading to thyroid gland enlargement and overactivity, with various symptoms affecting multiple organ systems, including thyroid-related skin conditions.
- The case presented involves an 11-year-old boy from Saudi Arabia with symptoms like goiter and bulging eyes, alongside unusual swelling and nodules on his body that resembled a lymphatic issue.
- Treatment options including steroid injections and total thyroid removal improved the patient's condition, highlighting the rare manifestations of thyroid dermopathy in this case.
Nephrotic syndrome: Pretibial epidermolysis bullosa in a patient with tetraspanin defect: A case report.
Int J Health Sci (Qassim)
January 2024
King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
Nephrotic syndrome (NS)-epidermolysis bullosa (EB) sensorineural deafness syndrome is an autosomal recessive rare genetic disease caused by a gene homozygous mutation on chromosome 11p15.5. In this report, we discuss a rare case related to a Saudi patient with genetic syndrome who presented with NS and EB.
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